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Advanced Search Results For "NEUTROPHILS"

1 - 10 of 159,382 results for
 "NEUTROPHILS"
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Transcriptional analysis of neutrophils from patients with Behçet's disease reveals activation and chemotaxis of neutrophils.

Publication Type: Academic Journal

Source(s): Clinical immunology (Orlando, Fla.) [Clin Immunol] 2022 Dec; Vol. 245, pp. 109161. Date of Electronic Publication: 2022 Oct 13.

Authors:

Abstract: Behçet's disease (BD) is a systemic vasculitis characterized by neutrophil activation with unclear pathogenesis. This study aimed to explore the transcriptional profiles of BD neutrophils and identify specific gene signatures. We performed RNA sequenci...

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Revealing key regulators of neutrophil function during inflammation by re-analysing single-cell RNA-seq.

Publication Type: Academic Journal

Source(s): PloS one [PLoS One] 2022 Oct 21; Vol. 17 (10), pp. e0276460. Date of Electronic Publication: 2022 Oct 21 (Print Publication: 2022).

Authors:

Abstract: Excessive neutrophil infiltration and dysfunction contribute to the progression and severity of hyper-inflammatory syndrome, such as in severe COVID19. In the current study, we re-analysed published scRNA-seq datasets of mouse and human neutrophils to ...

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What good can neutrophils do in UC?

Publication Type: Academic Journal

Source(s): Gut [Gut] 2022 Dec; Vol. 71 (12), pp. 2375-2376. Date of Electronic Publication: 2022 Jan 24.

Authors:

Abstract: Competing Interests: Competing interests: None declared.

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Early ultrastructural lesions of anti-neutrophil cytoplasmic antibody- versus complement-associated vasculitis.

Publication Type: Academic Journal

Source(s): Neuropathology : official journal of the Japanese Society of Neuropathology [Neuropathology] 2022 Oct; Vol. 42 (5), pp. 420-429. Date of Electronic Publication: 2022 Jun 15.

Abstract: This study aims to describe electron microscopic findings of vasculitis associated with anti-neutrophil cytoplasmic antibody (ANCA) and complement. Sural nerve biopsy specimens were obtained from 10 patients with microscopic polyangiitis (MPA), a repre...

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hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation.

Publication Type: Academic Journal

Source(s): Cells [Cells] 2022 Jul 30; Vol. 11 (15). Date of Electronic Publication: 2022 Jul 30.

Abstract: Neutrophils are not only crucial immune cells for the neutralization of pathogens during infections, but they are also key players in tissue repair and cancer. Several methods are available to investigate the in vivo role of neutrophils in these condit...

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C5a receptor antagonism coming of age for vascular pathology.

Publication Type: Academic Journal

Source(s): International immunopharmacology [Int Immunopharmacol] 2022 Sep; Vol. 110, pp. 109042. Date of Electronic Publication: 2022 Jul 14.

Abstract: The Food and Drug Administration recently approved the new drug avacopan for a relatively rare disease, anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis. Avacopan is an antagonist of receptor-1 for anaphylatoxin C5a (C5aR 1 ) that ...

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Lymph-derived chemokines direct early neutrophil infiltration in the lymph nodes upon Staphylococcus aureus skin infection.

Publication Type: Academic Journal

Source(s): Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Aug 09; Vol. 119 (32), pp. e2111726119. Date of Electronic Publication: 2022 Aug 01.

Authors:

Abstract: A large number of neutrophils infiltrate the lymph node (LN) within 4 h after Staphylococcus aureus skin infection (4 h postinfection [hpi]) and prevent systemic S. aureus dissemination. It is not clear how infection in the skin can remotely and effect...

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Neutrophils: New Critical Regulators of Glioma.

Publication Type: Academic Journal

Source(s): Frontiers in immunology [Front Immunol] 2022 Jul 04; Vol. 13, pp. 927233. Date of Electronic Publication: 2022 Jul 04 (Print Publication: 2022).

Authors:

Abstract: In cancer, neutrophils are an important part of the tumour microenvironment (TME). Previous studies have shown that circulating and infiltrating neutrophils are associated with malignant progression and immunosuppression in gliomas. However, recent stu...

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[The expression and clinical significance of neutrophil myeloperoxidase in patients with myeloperoxidase-antineutrophil cytoplasmic antibody associated vasculitis].

Publication Type: Academic Journal

Source(s): Zhonghua nei ke za zhi [Zhonghua Nei Ke Za Zhi] 2022 Sep 01; Vol. 61 (9), pp. 1016-1022.

Authors:

Abstract: Objective: To investigate the expression and clinical significance of neutrophil myeloperoxidase (MPO) in patients with MPO-antibody associated vasculitis (AAV). Methods: Thirty-six newly diagnosed MPO-AAV patients who were hospitalized in the First Af...

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CXCR2 Is Essential for Radiation-Induced Intestinal Injury by Initiating Neutrophil Infiltration.

Publication Type: Academic Journal

Source(s): Journal of immunology research [J Immunol Res] 2022 Jul 16; Vol. 2022, pp. 7966089. Date of Electronic Publication: 2022 Jul 16 (Print Publication: 2022).

Authors:

Abstract: Neutrophils, known as an important part of the immune system, are the most abundant leukocyte population in peripheral blood, but excessive recruitment will lead to tissue/organ injury. RNA sequencing showed that ionizing radiation significantly increa...

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