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Advanced Search Results For "NF-E2-Related Factor 2"

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 "NF-E2-Related Factor 2"
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Mangiferin Protects DNase 2 Abundance via Nrf2 Activation to Prevent Cytosolic mtDNA Accumulation during Liver Injury.

Publication Type: Academic Journal

Source(s): Molecular nutrition & food research [Mol Nutr Food Res] 2023 Jul; Vol. 67 (14), pp. e2200885. Date of Electronic Publication: 2023 May 25.

Authors:

Abstract: Scope: Mitochondrial DNA (mtDNA) released into the cytosol serves as a member of damage-associated molecular patterns to initiate inflammatory responses. Mangiferin is a xanthonoid derivative, usually isolated from plants including mangoes and iris ung...

Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.

Publication Type: Academic Journal

Source(s): Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Sep; Vol. 118, pp. 154954. Date of Electronic Publication: 2023 Jul 09.

Authors:

Abstract: Background: A type of gastric mucosal injury disease known as gastric ulcer (GU) is clearly connected to the aberrant release of gastric acid. Traditional botanicals have the potential for anti-inflammation, anti-oxidation, and other multitarget therap...

Fibroblast growth factor 10 alleviates acute lung injury by inhibiting excessive autophagy via Nrf2.

Publication Type: Academic Journal

Source(s): The Journal of endocrinology [J Endocrinol] 2023 Aug 17; Vol. 259 (1). Date of Electronic Publication: 2023 Aug 17 (Print Publication: 2023).

Authors:

Abstract: Acute lung injury (ALI) is associated with an increased incidence of respiratory diseases, which are devastating clinical disorders with high global mortality and morbidity. Evidence confirms that fibroblast growth factors (FGFs) play key roles in medi...

USP14 regulates heme metabolism and ovarian cancer invasion through BACH1 deubiquitination and stabilization.

Publication Type: Academic Journal

Source(s): Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jul 30; Vol. 667, pp. 186-193. Date of Electronic Publication: 2023 May 12.

Authors:

Abstract: The deubiquitinating enzyme USP14 has been established as a crucial regulator in various diseases, including tumors, neurodegenerative diseases, and metabolic diseases, through its ability to stabilize its substrate proteins. Our group has utilized pro...

Evaluation of Bach1 mRNA expression in patients with chronic kidney disease: A preliminary study.

Publication Type: Academic Journal

Source(s): Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2023 Jul; Vol. 27 (3), pp. 301-307. Date of Electronic Publication: 2023 Apr 03.

Abstract: Introduction: BTB and CNC homology 1 (Bach1) is a protein that antagonizes some actions of nuclear factor erythroid 2-related factor-2 (Nrf2), the master regulator of cytoprotective responses. Bach1 binds to genomic DNA and inhibits the synthesis of an...

Age and oxidative stress regulate Nrf2 homeostasis in human articular chondrocytes.

Publication Type: Academic Journal

Source(s): Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2023 Sep; Vol. 31 (9), pp. 1214-1223. Date of Electronic Publication: 2023 May 07.

Abstract: Objective: The purpose of this study was to investigate the effect of age and oxidative stress on regulation of nuclear factor erythroid-2-related factor 2 (Nrf2) in young, old, and osteoarthritic (OA) human articular chondrocytes.Design: Levels of Nrf...

Panax quinquefolius saponin inhibits vascular smooth muscle cell calcification via activation of nuclear factor-erythroid 2-related factor 2.

Publication Type: Academic Journal

Source(s): BMC complementary medicine and therapies [BMC Complement Med Ther] 2023 Apr 21; Vol. 23 (1), pp. 129. Date of Electronic Publication: 2023 Apr 21.

Authors:

Abstract: Background: Panax quinquefolius saponin (PQS) is the main active component of Panax quinquefolius. Emerging evidence suggests that PQS exerts beneficial effects against cardiovascular diseases. However, the role and mechanism of PQS in vascular calcifi...

Whey Protein Hydrolysate Ameliorated High-Fat-Diet Induced Bone Loss via Suppressing Oxidative Stress and Regulating GSK-3β/Nrf2 Signaling Pathway.

Publication Type: Academic Journal

Source(s): Nutrients [Nutrients] 2023 Jun 24; Vol. 15 (13). Date of Electronic Publication: 2023 Jun 24.

Authors:

Abstract: Long-term hypercaloric intake such as a high-fat diet (HFD) could act as negative regulators on bone remodeling, thereby inducing bone loss and bone microarchitecture destruction. Currently, food-derived natural compounds represent a promising strategy...

Ruscogenin timing administration mitigates cerebral ischemia-reperfusion injury through regulating circadian genes and activating Nrf2 pathway.

Publication Type: Academic Journal

Source(s): Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Nov; Vol. 120, pp. 155028. Date of Electronic Publication: 2023 Aug 20.

Authors:

Abstract: Background: Ruscogenin (Rus), a steroidal sapogenin extracted from Ophiopogon japonicus (L. f.) Ker-Gawl., has the effect of alleviating cerebral ischemia-reperfusion injury (IRI), acute lung injury. At present, the chronopharmacological effects of Rus...

Long-term detraining reverses the improvement of lifelong exercise on skeletal muscle ferroptosis and inflammation in aging rats: fiber-type dependence of the Keap1/Nrf2 pathway.

Publication Type: Academic Journal

Source(s): Biogerontology [Biogerontology] 2023 Oct; Vol. 24 (5), pp. 753-769. Date of Electronic Publication: 2023 Jun 08.

Authors:

Abstract: We investigated the effects of lifelong aerobic exercise and 8 months of detraining after 10 months of aerobic training on circulation, skeletal muscle oxidative stress, and inflammation in aging rats. Sprague-Dawley rats were randomly assigned to the ...

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