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Histopathological Overview of Experimental Ulcer Models.
Publication Type: Academic Journal
Source(s): Eurasian Journal of Medicine. 2022 Supplement, Vol. 54, pS120-S126. 7p.
Abstract: Histopathology is the process of examining tissue that includes all the changes, when a diseased tissue shows compared to a healthy group with a result of a histological observation. Histopathology has become an essential process in medical experimenta...
Nano-curcumin Attenuates Nephropathic Lesions Induced by Chronic Ketoprofen Administration in Rats: Role of Cyclooxygenase-1.
Publication Type: Academic Journal
Source(s): Journal of Advanced Veterinary Research. Oct2022, Vol. 12 Issue 5, p524-534. 11p.
Abstract: Ketoprofen can relieve pain and inflammation associated with many diseases but, it may cause unwanted side effects especially in kidneys. Curcumin nanoparticles (CurNPs) have a protective effect related to their anti-inflammatory and antioxidant proper...
OPIOID MODULATION OF ANTINOCICEPTION OF CELECOXIB AND KETOROLAC AT PRE-CLINICAL PAIN.
Publication Type: Academic Journal
Source(s): Journal of Experimental Research. Jun2022, Vol. 10 Issue 2, p81-88. 8p.
Abstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat pain, fever, and inflammation. Among them are celecoxib and ketorolac, whose efficacy is dependent on the inhibition of COXs and seems to be modulated by additional mechanisms that would c...
Adsorptive Removal of Ibuprofen, Ketoprofen and Naproxen from Aqueous Solution Using Coconut Shell Biomass.
Publication Type: Academic Journal
Source(s): Environmental Research, Engineering & Management. 2022, Vol. 78 Issue 2, p28-37. 10p.
Abstract: The use of commercial activated carbon (AC) to remove organic micropollutants from aqueous solution is expensive and unsustainable. In this study, coconut shell activated carbon (CSAC) was synthesized and applied for the removal of ibuprofen, ketoprofe...
NSAIDs in COVID-19, friend or foe?
Publication Type: Academic Journal
Source(s): Anaesthesia, Pain & Intensive Care. Aug2022, Vol. 26 Issue 4, p427-429. 3p.
Abstract: At the beginning of COVID-19 pandemic the use of NSAIDS was avoided. This was because the previous studies suggesting that NSAIDs may be linked to an increased risk of lower respiratory tract infection consequences. Later on studies involved the patien...
Synthesis of some novel hydrazide-hydrazones derived from etodolac as potential anti-prostate cancer agents.
Publication Type: Academic Journal
Source(s): Journal of Research in Pharmacy. 2022, Vol. 26 Issue 1, p1-12. 12p.
Abstract: R,S)-Etodolac [1,8-diethyl-1,3,4,9-tetrahydrapyrano(3,4-b)indole-1-acetic acid] is a nonsteroidal antiinflammatory drug that contains carboxylic acid group with the structure of pyrano[3,4-b]indole. In this study, a series of novel (R,S)-Etodolac deriv...
Characterising risk of non-steroidal anti-inflammatory drug-related acute kidney injury: a retrospective cohort study.
Publication Type: Academic Journal
Source(s): BJGP Open. Mar2022, Vol. 6 Issue 1, p1-11. 11p.
Abstract: Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed for pain and inflammation. NSAID complications include acute kidney injury (AKI), causing burden to patients and health services through increased morbidity, mortality, ...
- CONFIDENCE intervals
- NONSTEROIDAL anti-inflammatory agents
- RETROSPECTIVE studies
- CARDIOVASCULAR diseases
- SOCIOECONOMIC factors
- RISK assessment
- DESCRIPTIVE statistics
- DRUG prescribing
- RESEARCH funding
- LOGISTIC regression analysis
- PHYSICIAN practice patterns
- ODDS ratio
- ACUTE kidney failure
- LONGITUDINAL method
- COMORBIDITY
- HEART failure
- DISEASE risk factors
Enhanced NSAIDs Solubility in Drug–Drug Formulations with Ciprofloxacin †.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 4, p3305. 19p.
Abstract: Drug–drug salts are a kind of pharmaceutical multicomponent solid in which the two co-existing components are active pharmaceutical ingredients (APIs) in their ionized forms. This novel approach has attracted great interest in the pharmaceutical indust...
Coprecipitation of Class II NSAIDs with Polymers for Oral Delivery.
Publication Type: Academic Journal
Source(s): Polymers (20734360). Feb2023, Vol. 15 Issue 4, p954. 15p.
Abstract: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently administered orally with modified-release formulations. The attainment of modified-release drugs is commonly achieved through the coprecipitation of the active principle with a biodegradable...
Exploration of the Safety and Solubilization, Dissolution, Analgesic Effects of Common Basic Excipients on the NSAID Drug Ketoprofen.
Publication Type: Academic Journal
Source(s): Pharmaceutics. Feb2023, Vol. 15 Issue 2, p713. 15p.
Abstract: Since its introduction to the market in the 1970s, ketoprofen has been widely used due to its high efficacy in moderate pain management. However, its poor solubility and ulcer side effects have diminished its popularity. This study prepared forms of ke...