Advanced Search Results For "Neuroprotective Agents"
Your filters
NLRP3 mediates the neuroprotective effects of SVHRSP derived from scorpion venom in rotenone-induced experimental Parkinson's disease model.
Publication Type: Academic Journal
Source(s): Journal of ethnopharmacology [J Ethnopharmacol] 2023 Aug 10; Vol. 312, pp. 116497. Date of Electronic Publication: 2023 Apr 16.
Abstract: Ethnopharmacological Relevance: In traditional Chinese medicine, scorpion is used to treat diseases with symptoms such as trembling, convulsion and dementia. Our laboratory employs patented technology to extract and purify the active single component f...
Anti-inflammatory, anti-apoptotic, and neuroprotective potentials of anethole in Parkinson's disease-like motor and non-motor symptoms induced by rotenone in rats.
Publication Type: Academic Journal
Source(s): Metabolic brain disease [Metab Brain Dis] 2023 Aug; Vol. 38 (6), pp. 2159-2174. Date of Electronic Publication: 2023 May 19.
Abstract: Parkinson's disease (PD) is a complex neurological disorder characterized by a combination of motor and non-motor symptoms (NMS). Antioxidant and anti-inflammatory compounds are considered a potential therapeutic strategy against PD. The present study ...
Antidiabetic agents as a novel treatment for Alzheimer's and Parkinson's disease.
Publication Type: Academic Journal
Source(s): Ageing research reviews [Ageing Res Rev] 2023 Aug; Vol. 89, pp. 101979. Date of Electronic Publication: 2023 Jun 14.
Abstract: Therapeutic strategies for neurodegenerative disorders have commonly targeted individual aspects of the disease pathogenesis to little success. Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characteriz...
Neuroprotective effects of photobiomodulation by hormesis on scopolamine induced neurodegenerative diseases of memory disorders in rats a paradigm shift.
Publication Type: Academic Journal
Source(s): Journal of biophotonics [J Biophotonics] 2023 Aug; Vol. 16 (8), pp. e202300012. Date of Electronic Publication: 2023 May 05.
Abstract: The loss and progressive dysfunction of neurons are hallmarks of neurodegenerative diseases. The aim of the current study is to explore the effects of photobiomodulation at 460-660 nm (100-1000 lux units) on the progression of scopolamine-induced cogni...
m -Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity.
Publication Type: Academic Journal
Source(s): Molecules (Basel, Switzerland) [Molecules] 2023 Jul 13; Vol. 28 (14). Date of Electronic Publication: 2023 Jul 13.
Abstract: Inhibition of cyclooxygenase-2 (COX-2) has been extensively studied as an approach to reduce proinflammatory markers in acute brain diseases, but the anti-neuroinflammatory role of cyclooxygenase-1 (COX-1) inhibition has been rather neglected. We repor...
Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury.
Publication Type: Academic Journal
Source(s): ACS nano [ACS Nano] 2023 Jul 11; Vol. 17 (13), pp. 12176-12187. Date of Electronic Publication: 2023 Jun 30.
Abstract: Spinal cord injury (SCI), which is characterized by excessive inflammatory cell infiltration and accumulation of oxidative substance, would severely impede neurological functional recovery and lead to permanent and profound neurologic deficits and even...
From the Bush to the Brain: Preclinical Stages of Ethnobotanical Anti-Inflammatory and Neuroprotective Drug Discovery-An Australian Example.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jul 04; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 04.
Abstract: The Australian rainforest is a rich source of medicinal plants that have evolved in the face of dramatic environmental challenges over a million years due to its prolonged geographical isolation from other continents. The rainforest consists of an inhe...
Neuroprotective effect of quercetin and nano-quercetin against cyclophosphamide-induced oxidative stress in the rat brain: Role of Nrf2/ HO-1/Keap-1 signaling pathway.
Publication Type: Academic Journal
Source(s): Neurotoxicology [Neurotoxicology] 2023 Sep; Vol. 98, pp. 16-28. Date of Electronic Publication: 2023 Jul 06.
Abstract: Quercetin (Qu) is a powerful flavanol antioxidant that is naturally found in plants and is part of the flavonoid family. Qu has a wide range of biological properties, such as neuroprotective, anti-cancer, anti-diabetic, anti-inflammatory, and radical s...
18β-glycyrrhetinic acid ameliorates MPTP-induced neurotoxicity in mice through activation of microglial anti-inflammatory phenotype.
Publication Type: Academic Journal
Source(s): Psychopharmacology [Psychopharmacology (Berl)] 2023 Sep; Vol. 240 (9), pp. 1947-1961. Date of Electronic Publication: 2023 Jul 12.
Abstract: Rationale: 18β-glycyrrhetinic acid (18β-GA) has been reported to have anti-inflammatory and neuroprotective effects. However, the therapeutic effect of 18β-GA in Parkinson's disease (PD) has not been defined.Objective: The current study aimed to evalua...
Novel flavonoid 1,3,4-oxadiazole derivatives ameliorate MPTP-induced Parkinson's disease via Nrf2/NF-κB signaling pathway.
Publication Type: Academic Journal
Source(s): Bioorganic chemistry [Bioorg Chem] 2023 Sep; Vol. 138, pp. 106654. Date of Electronic Publication: 2023 Jun 03.
Abstract: Parkinson's disease (PD) is a progressive neurodegenerative disorder with a complex etiology. Neuroinflammation and oxidative stress are important factors driving the progression of PD. It has been reported that 1,3,4-oxadiazole and flavone derivatives...