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Low-Dose 0.01% Atropine Eye Drops vs Placebo for Myopia Control: A Randomized Clinical Trial.
Publication Type: Academic Journal
Source(s): JAMA ophthalmology [JAMA Ophthalmol] 2023 Aug 01; Vol. 141 (8), pp. 756-765.
Abstract: Importance: Controlling myopia progression is of interest worldwide. Low-dose atropine eye drops have slowed progression in children in East Asia.Objective: To compare atropine, 0.01%, eye drops with placebo for slowing myopia progression in US childre...
Effect of Low-Concentration Atropine Eyedrops vs Placebo on Myopia Incidence in Children: The LAMP2 Randomized Clinical Trial.
Publication Type: Academic Journal
Source(s): JAMA [JAMA] 2023 Feb 14; Vol. 329 (6), pp. 472-481.
Abstract: Importance: Early onset of myopia is associated with high myopia later in life, and myopia is irreversible once developed.Objective: To evaluate the efficacy of low-concentration atropine eyedrops at 0.05% and 0.01% concentration for delaying the onset...
Hydrogel eye drops as a non-invasive drug carrier for topical enhanced Adalimumab permeation and highly efficient uveitis treatment.
Publication Type: Academic Journal
Source(s): Carbohydrate polymers [Carbohydr Polym] 2021 Feb 01; Vol. 253, pp. 117216. Date of Electronic Publication: 2020 Oct 13.
Abstract: Uveitis is one of the most popular blind-causing eye diseases worldwide. Adalimumab (ADA) is used for the uveitis treatment through systemic or intravitreal injection at the expense of systemic side effects and increased medical risks. Although eye dro...
Nanotechnology for Topical Drug Delivery to the Anterior Segment of the Eye.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2021 Nov 16; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 16.
Abstract: Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are the most prevalent drug form, especially for widely distributed anterior segment eye diseases (cataracts, glaucoma, dry eye syndrome, inflammatory diseases, etc....
Desquamating pustular rash.
Publication Type: Academic Journal
Source(s): Cleveland Clinic journal of medicine [Cleve Clin J Med] 2019 Dec; Vol. 86 (12), pp. 780-781.
VEGF-A in Serum and Plasma Rich in Growth Factors (PRGF) Eye Drops.
Publication Type: Academic Journal
Source(s): Klinische Monatsblatter fur Augenheilkunde [Klin Monbl Augenheilkd] 2022 Apr; Vol. 239 (4), pp. 378-381. Date of Electronic Publication: 2022 Apr 26.
Abstract: Background: Vascular endothelial growth factor (VEGF)-A, the most abundant subtype of the VEGF family in the eye, plays an important role in corneal homeostasis due to its ability to mediate corneal nerve repair. Repeated intravitreal anti-VEGF injecti...
Validation of a More Reliable Method of Eye Drop Self-Administration.
Publication Type: Academic Journal
Source(s): Optometry and vision science : official publication of the American Academy of Optometry [Optom Vis Sci] 2020 Jul; Vol. 97 (7), pp. 496-502.
Abstract: Significance: We propose an alternative method for eye drop self-administration. Similar IOP reductions were found with this method compared with clinician instillation. The alternative method of self-administration potentially benefits patients who ha...
New Classes of Polycationic Compounds as Preservatives for Ophthalmic Formulations.
Publication Type: Academic Journal
Source(s): Pharmaceutical research [Pharm Res] 2018 Nov 08; Vol. 36 (1), pp. 11. Date of Electronic Publication: 2018 Nov 08.
Abstract: Purpose: The purpose of this research work was to develop new polycationic compounds based on pyridine and piperidine structures with high antimicrobial activities against bacteria and fungi. Furthermore, the compounds should offer a lower toxicity tha...
Ocular pharmacokinetics of atenolol, timolol and betaxolol cocktail: Tissue exposures in the rabbit eye.
Publication Type: Academic Journal
Source(s): European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2021 Sep; Vol. 166, pp. 155-162. Date of Electronic Publication: 2021 Jun 15.
Abstract: Quantitative understanding of pharmacokinetics of topically applied ocular drugs requires more research to further understanding and to eventually allow predictive in silico models to be developed. To this end, a topical cocktail of betaxolol, timolol ...