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Advanced Search Results For "PRAGMATICS"

1 - 10 of 16,401 results for
 "PRAGMATICS"
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The Electronic Health Record as the Primary Data Source in a Pragmatic Trial: A Case Study.

Publication Type: Academic Journal

Source(s): Medical decision making : an international journal of the Society for Medical Decision Making [Med Decis Making] 2022 Nov; Vol. 42 (8), pp. 975-984. Date of Electronic Publication: 2022 Jan 12.

Abstract: Highlights: Electronic health records are not a single system but a series of overlapping and legacy systems that require time and expertise to use efficiently.Commonly measured patient characteristics such as weight and body mass index are relatively ...

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Heterogeneity in pragmatic randomised trials: sources and management.

Publication Type: Academic Journal

Source(s): BMC medicine [BMC Med] 2022 Oct 28; Vol. 20 (1), pp. 372. Date of Electronic Publication: 2022 Oct 28.

Abstract: Background: Pragmatic trials aim to generate evidence to directly inform patient, caregiver and health-system manager policies and decisions. Heterogeneity in patient characteristics contributes to heterogeneity in their response to the intervention. H...

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Patient responses to passive enrollment into a large, pragmatic clinical trial: A qualitative content analysis.

Publication Type: Academic Journal

Source(s): Contemporary clinical trials [Contemp Clin Trials] 2022 Oct; Vol. 121, pp. 106925. Date of Electronic Publication: 2022 Sep 13.

Abstract: Background: While passive enrollment or "opt-out" recruitment methods facilitate pragmatic clinical trials, they pose unique challenges, and it is unclear how participants feel about them. Here, we describe patient responses to passive enrollment into ...

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Pragmatic clinical trial design in emergency medicine: Study considerations and design types.

Publication Type: Academic Journal

Source(s): Academic emergency medicine : official journal of the Society for Academic Emergency Medicine [Acad Emerg Med] 2022 Oct; Vol. 29 (10), pp. 1247-1257. Date of Electronic Publication: 2022 May 22.

Abstract: Pragmatic clinical trials (PCTs) focus on correlation between treatment and outcomes in real-world clinical practice, yet a guide highlighting key study considerations and design types for emergency medicine investigators pursuing this important study ...

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Ethics and regulatory complexities posed by a pragmatic clinical trial: a case study from Lilongwe, Malawi.

Publication Type: Academic Journal

Source(s): Malawi medical journal : the journal of Medical Association of Malawi [Malawi Med J] 2022 Sep; Vol. 34 (3), pp. 213-219.

Abstract: Background: Pragmatic clinical trials generally rely on real world data and have the potential to generate real world evidence. This approach arose from concerns that many trial results did not adequately inform real world practice. However, maintainin...

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Identifying physician-perceived barriers to a pragmatic treatment trial in rheumatoid arthritis.

Publication Type: Academic Journal

Source(s): European journal of rheumatology [Eur J Rheumatol] 2022 Jul; Vol. 9 (3), pp. 132-138.

Abstract: Objective: The aim of this qualitative research was to identify physician-perceived patient and clinic barriers to patient recruitment in a rheumatoid arthritis (RA) pragmatic trial of anti-tumor necrosis factor (TNF) biologic versus non-TNF biologic/J...

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Optimizing the Impact of Pragmatic Clinical Trials for Veteran and Military Populations: Lessons From the Pain Management Collaboratory.

Publication Type: Academic Journal

Source(s): Military medicine [Mil Med] 2022 Jul 01; Vol. 187 (7-8), pp. 179-185.

Abstract: Pragmatic clinical trials (PCTs) are well-suited to address unmet healthcare needs, such as those arising from the dual public health crises of chronic pain and opioid misuse, recently exacerbated by the COVID-19 pandemic. These overlapping epidemics h...

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The impact of COVID-19 on pragmatic clinical trials: lessons learned from the NIH Health Care Systems Research Collaboratory.

Publication Type: Academic Journal

Source(s): Trials [Trials] 2022 May 21; Vol. 23 (1), pp. 424. Date of Electronic Publication: 2022 May 21.

Abstract: Background: The COVID-19 pandemic has considerably disrupted nearly all aspects of daily life, including healthcare delivery and clinical research. Because pragmatic clinical trials are often embedded within healthcare delivery systems, they may be at ...

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Ethical and epistemic issues in the design and conduct of pragmatic stepped-wedge cluster randomized clinical trials.

Publication Type: Academic Journal

Source(s): Contemporary clinical trials [Contemp Clin Trials] 2022 Apr; Vol. 115, pp. 106703. Date of Electronic Publication: 2022 Feb 15.

Abstract: Stepped-wedge cluster randomized trial (SW-CRT) designs are increasingly employed in pragmatic research; they differ from traditional parallel cluster randomized trials in which an intervention is delivered to a subset of clusters, but not to all. In a...

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Developing lay summaries and thank you notes in paediatric pragmatic clinical trials.

Publication Type: Academic Journal

Source(s): Health expectations : an international journal of public participation in health care and health policy [Health Expect] 2022 Jun; Vol. 25 (3), pp. 1029-1037. Date of Electronic Publication: 2022 Mar 04.

Abstract: Introduction: Better transparency of research results and participant engagement may help address poor participant accrual in paediatric clinical research. We conducted formative research to assess the acceptability of lay summaries and thank you notes...

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