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Advanced Search Results For "QH573-671"

1 - 10 of 23,917 results for
 "QH573-671"
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Molecular mechanisms of microRNA-216a during tumor progression

Publication Type: Academic Journal

Source(s): Cancer Cell International, Vol 23, Iss 1, Pp 1-18 (2023)

Abstract: Abstract MicroRNAs (miRNAs) as the members of non-coding RNAs family are involved in post-transcriptional regulation by translational inhibiting or mRNA degradation. They have a critical role in regulation of cell proliferation and migration. MiRNAs ab...

BRAFV600E mutational status assessment in cutaneous melanocytic neoplasms in a group of the Egyptian population

Publication Type: Academic Journal

Source(s): Cancer Cell International, Vol 23, Iss 1, Pp 1-9 (2023)

Abstract: Abstract Background Melanocytic neoplasms range from banal nevi to malignant melanomas. The genetic background has been extensively studied in the Caucasian population. BRAF mutations were reported among the early driver mutations in nevogenesis. Never...

Environmental signals perceived by the brain abate pro-metastatic monocytes by dampening glucocorticoids receptor signaling

Publication Type: Academic Journal

Source(s): Cancer Cell International, Vol 23, Iss 1, Pp 1-16 (2023)

Abstract: Abstract While positive social-behavioral factors predict longer survival in cancer patients, the underlying mechanisms are unknown. Since tumor metastasis are the major cancer mortality factor, we investigated how an enriched environment (EE) conducti...

A review on the role of long non-coding RNA and microRNA network in clear cell renal cell carcinoma and its tumor microenvironment

Publication Type: Academic Journal

Source(s): Cancer Cell International, Vol 23, Iss 1, Pp 1-22 (2023)

Abstract: Abstract Renal cell carcinoma (RCC) is the second lethal urogenital malignancy with the increasing incidence and mortality in the world. Clear cell renal cell carcinoma (ccRCC) is one major subtype of RCC, which accounts for about 70 to 80% of all RCC ...

Changes in HER3 expression profiles between primary and recurrent gynecological cancers

Publication Type: Academic Journal

Source(s): Cancer Cell International, Vol 23, Iss 1, Pp 1-9 (2023)

Abstract: Abstract Background Human epidermal growth factor receptor-3 (HER3) is a member of the epidermal growth factor receptor family of receptor tyrosine kinases, and its overexpression is associated with inferior prognosis in several cancers. However, it is...

VHL-HIF-2α axis-induced SEMA6A upregulation stabilized β-catenin to drive clear cell renal cell carcinoma progression

Publication Type: Academic Journal

Source(s): Cell Death and Disease, Vol 14, Iss 2, Pp 1-10 (2023)

Abstract: Abstract SEMA6A is a multifunctional transmembrane semaphorin protein that participates in various cellular processes, including axon guidance, cell migration, and cancer progression. However, the role of SEMA6A in clear cell renal cell carcinoma (ccRC...

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Non-canonical functions of spliceosome components in cancer progression

Publication Type: Academic Journal

Source(s): Cell Death and Disease, Vol 14, Iss 2, Pp 1-17 (2023)

Abstract: Abstract Dysregulation of pre-mRNA splicing is a common hallmark of cancer cells and it is associated with altered expression, localization, and mutations of the components of the splicing machinery. In the last few years, it has been elucidated that s...

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SARS-CoV-2 infection induces persistent adipose tissue damage in aged golden Syrian hamsters

Publication Type: Academic Journal

Source(s): Cell Death and Disease, Vol 14, Iss 2, Pp 1-16 (2023)

Abstract: Abstract Coronavirus disease 2019 (COVID-19, caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)) is primarily a respiratory illness. However, various extrapulmonary manifestations have been reported in patients with severe forms of ...

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CCN3/NOV promotes metastasis and tumor progression via GPNMB-induced EGFR activation in triple-negative breast cancer

Publication Type: Academic Journal

Source(s): Cell Death and Disease, Vol 14, Iss 2, Pp 1-16 (2023)

Abstract: Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. TNBC patients typically exhibit unfavorable outcomes due to its rapid growth and metastatic potential. Here, we found overexpression of CCN3 in TNBC patients...

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Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

Publication Type: Academic Journal

Source(s): Cell Death and Disease, Vol 14, Iss 2, Pp 1-13 (2023)

Abstract: Abstract Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epige...

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