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Erdheim-Chester disease associated with an aggressive form of sclerosing cholangitis
Publication Type: Academic Journal
Source(s): Egyptian Liver Journal, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract: Abstract Background Erdheim-Chester disease (ECD) is a rare histiocytic disorder recently recognized as a neoplasm due to the discovery of activating MAPK pathway mutations. Hepatic involvement by ECD is extremely rare. Case presentation We describe a ...
Alcohol treatment discussions and clinical outcomes among patients with alcohol-related cirrhosis
Publication Type: Academic Journal
Source(s): BMC Gastroenterology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract: Abstract Background Alcohol cessation is the cornerstone of treatment for alcohol-related cirrhosis. This study evaluated associations between medical conversations about alcohol use disorder (AUD) treatment, AUD treatment engagement, and mortality. Me...
Real-world systemic sequential therapy with regorafenib for recurrent hepatocellular carcinoma: analysis of 93 cases from a single center
Publication Type: Academic Journal
Source(s): BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract: Abstract Background Regorafenib is an oral multikinase inhibitor and became the first second-line systemic treatment for hepatocellular carcinoma (HCC) following the phase III RESORCE trial. This single-center study retrospectively analyzed the clinica...
Future Perspectives in the Diagnosis and Treatment of Liver Disease Associated with Alpha-1 Antitrypsin Deficiency
Publication Type: Academic Journal
Source(s): GE: Portuguese Journal of Gastroenterology, Pp 1-9 (2023)
Abstract: Alpha-1 antitrypsin deficiency (AATD) is one of the most common genetic diseases and is caused by mutations in the SERPINA1 gene. The homozygous Pi*Z variant is responsible for the majority of the classic severe form of alpha-1 antitrypsin deficiency, ...
Analysis of related factors of portal vein thrombosis in liver cirrhosis
Publication Type: Academic Journal
Source(s): BMC Gastroenterology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract: Abstract Background and aims To investigate the usefulness of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), protein C (PC), and thromboelastography (TEG) to serve as a predictor of portal vein thrombosis (PVT) in patients with liver cirrho...
Progression of Recurrent Pancreatitis to Chronic Pancreatitis within 3 Years due to SPINK1 Mutation IVS3+2T>C
Publication Type: Academic Journal
Source(s): Case Reports in Gastroenterology, Vol 17, Iss 1, Pp 55-61 (2023)
Abstract: When the etiology of pancreatitis cannot be determined despite sufficient investigation, recurrence and progression to chronic pancreatitis often involve genetic mutations. Herein, we describe a case of recurrent pancreatitis with the IVS3+2T>C mutatio...
A Patient with Transverse Colon Cancer Complicated by Cowden Syndrome Administered FOLFOXIRI + Bevacizumab Therapy
Publication Type: Academic Journal
Source(s): Case Reports in Gastroenterology, Vol 17, Iss 1, Pp 62-69 (2023)
Abstract: Cowden syndrome is characterized by several clinical features related to tumorous lesions primarily consisting of systemic hamartomas. The mutation of a tumor suppressor gene, the PTEN gene, is etiologically involved. As gastrointestinal lesions, polyp...
Expanding the treatment of chronic hepatitis B
Publication Type: Academic Journal
Source(s): Linchuang Gandanbing Zazhi, Vol 39, Iss 1, Pp 10-13 (2023)
Thoughts on expert opinion on expanding antiviral therapy for chronic hepatitis B
Publication Type: Academic Journal
Source(s): Linchuang Gandanbing Zazhi, Vol 39, Iss 1, Pp 14-21 (2023)
Abstract: Expanding antiviral therapy is currently the new trend for the diagnosis and treatment of chronic hepatitis B, and related research evidence should be studied and discussed. Reducing the threshold of alanine aminotransferase (ALT) for initiating antivi...
Expanding the indications for antiviral therapy for chronic hepatitis B: Advantages and disadvantages
Publication Type: Academic Journal
Source(s): Linchuang Gandanbing Zazhi, Vol 39, Iss 1, Pp 22-26 (2023)
Abstract: Chronic hepatitis B (CHB) is a chronic progressive disease caused by hepatitis B virus (HBV), and without timely and effective antiviral therapy, it will eventually develop into liver cirrhosis, liver failure or hepatocellular carcinoma (HCC). Early in...