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RNA circuits and RNA-binding proteins in T cells.
Publication Type: Academic Journal
Source(s): Trends in immunology [Trends Immunol] 2023 Oct; Vol. 44 (10), pp. 792-806. Date of Electronic Publication: 2023 Aug 18.
Abstract: RNA is integral to the regulatory circuits that control cell identity and behavior. Cis-regulatory elements in mRNAs interact with RNA-binding proteins (RBPs) that can alter RNA sequence, stability, and translation into protein. Similarly, long noncodi...
Differential Expression of miRNAs, lncRNAs, and circRNAs between Ovaries and Testes in Common Carp ( Cyprinus carpio ).
Publication Type: Academic Journal
Source(s): Cells [Cells] 2023 Nov 15; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 15.
Abstract: Female common carp grow faster than male individuals, implying that rearing females could be more profitable in aquaculture. Non-coding RNAs (ncRNAs) serve as versatile regulators with multiple functions in diverse biological processes. However, the ro...
Insights into the structure and function of the RNA ligase RtcB.
Publication Type: Academic Journal
Source(s): Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2023 Nov 07; Vol. 80 (12), pp. 352. Date of Electronic Publication: 2023 Nov 07.
Abstract: To be functional, some RNAs require a processing step involving splicing events. Each splicing event necessitates an RNA ligation step. RNA ligation is a process that can be achieved with various intermediaries such as self-catalysing RNAs, 5'-3' and 3...
Comparative Transcriptomic Profiling in Ovarian Tissues of Lohmann Hens and Chengkou Mountain Chicken.
Publication Type: Academic Journal
Source(s): Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2023 Oct 26; Vol. 28 (10), pp. 267.
Abstract: Background: As a crucial economic characteristic and a major indicator of reproductive performance in layers, egg production is controlled by a series of complex regulatory heredity basis. In particular, the interacting regulatory function between nonc...
Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K.
Publication Type: Academic Journal
Source(s): ELife [Elife] 2023 Oct 03; Vol. 12. Date of Electronic Publication: 2023 Oct 03.
Abstract: Eukaryotic genes are interrupted by introns that are removed from transcribed RNAs by splicing. Patterns of splicing complexity differ between species, but it is unclear how these differences arise. We used inter-species association mapping with Saccha...
Development of Engineered-U1 snRNA Therapies: Current Status.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Sep 27; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 27.
Abstract: Splicing of pre-mRNA is a crucial regulatory stage in the pathway of gene expression. The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. ...
RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size.
Publication Type: Academic Journal
Source(s): Cell [Cell] 2023 Nov 22; Vol. 186 (24), pp. 5254-5268.e26. Date of Electronic Publication: 2023 Nov 08.
Abstract: A fundamental feature of cellular growth is that total protein and RNA amounts increase with cell size to keep concentrations approximately constant. A key component of this is that global transcription rates increase in larger cells. Here, we identify...
RNA pseudouridine modification in plants.
Publication Type: Academic Journal
Source(s): Journal of experimental botany [J Exp Bot] 2023 Nov 21; Vol. 74 (21), pp. 6431-6447.
Abstract: Pseudouridine is one of the well-known chemical modifications in various RNA species. Current advances to detect pseudouridine show that the pseudouridine landscape is dynamic and affects multiple cellular processes. Although our understanding of this ...
Whole-Transcriptome RNA Sequencing Uncovers the Global Expression Changes and RNA Regulatory Networks in Duck Embryonic Myogenesis.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Nov 16; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 16.
Abstract: Duck meat is pivotal in providing high-quality protein for human nutrition, underscoring the importance of studying duck myogenesis. The regulatory mechanisms governing duck myogenesis involve both coding and non-coding RNAs, yet their specific express...
Identification and quantification of small exon-containing isoforms in long-read RNA sequencing data.
Publication Type: Academic Journal
Source(s): Nucleic acids research [Nucleic Acids Res] 2023 Nov 10; Vol. 51 (20), pp. e104.
Abstract: Small exons are pervasive in transcriptomes across organisms, and their quantification in RNA isoforms is crucial for understanding gene functions. Although long-read RNA-seq based on Oxford Nanopore Technologies (ONT) offers the advantage of covering ...