Advanced Search Results For "Receptor for Advanced Glycation End Products"
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Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes.
Publication Type: Academic Journal
Source(s): Scientific reports [Sci Rep] 2023 Aug 09; Vol. 13 (1), pp. 12948. Date of Electronic Publication: 2023 Aug 09.
Abstract: Hypoglycemia in type 1 diabetes associates with changes in the pancreatic islet α cells, where the receptor for advanced glycation end products (RAGE) is highly expressed. This study compared islet RAGE expression in donors without diabetes, those at r...
Evidence that methylglyoxal and receptor for advanced glycation end products are implicated in bladder dysfunction of obese diabetic ob / ob mice.
Publication Type: Academic Journal
Source(s): American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2023 Oct 01; Vol. 325 (4), pp. F436-F447. Date of Electronic Publication: 2023 Aug 10.
Abstract: Glycolytic overload in diabetes causes large accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO) and overproduction of advanced glycation end products (AGEs), which interact with their receptors (RAGE), leading to diabetes-assoc...
Receptor for Advanced Glycation End Products: Dementia and Cognitive Impairment.
Publication Type: Academic Journal
Source(s): Drug research [Drug Res (Stuttg)] 2023 Jun; Vol. 73 (5), pp. 247-250. Date of Electronic Publication: 2023 Mar 08.
Abstract: The pathophysiological processes of dementia and cognitive impairment are linked to advanced glycation end products (AGEs) and their receptor (RAGE).The neurofibrillary tangles (NFTs) of abnormally hyperphosphorylated tau protein and senile plaques (SP...
Role of profilin-1 in vasculopathy induced by advanced glycation end products (AGEs).
Publication Type: Academic Journal
Source(s): Journal of diabetes and its complications [J Diabetes Complications] 2023 May; Vol. 37 (5), pp. 108415. Date of Electronic Publication: 2023 Feb 04.
Abstract: Aims: To construct a simple and feasible rat model to mimic diabetic vasculopathy by chronic injection of advanced glycation end products (AGEs) and further determine the role of profilin-1 in vasculopathy in AGE-injection rats.Methods: Sprague-Dawley ...
Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway.
Publication Type: Academic Journal
Source(s): Molecular biology reports [Mol Biol Rep] 2023 Jul; Vol. 50 (7), pp. 5849-5858. Date of Electronic Publication: 2023 May 25.
Abstract: Background: Advanced glycation end products (AGEs) are heterogeneous proinflammatory molecules produced by a non-enzymatic glycation reaction between reducing sugars (and their metabolites) and biomolecules with amino groups, such as proteins. Although...
Receptor for the Advanced Glycation End Products ( RAGE ) Pathway in Adipose Tissue Metabolism.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jul 01; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 01.
Abstract: Advanced glycation end products (AGEs) are mediators in the process of cellular dysfunction in response to hyperglycemia. Numerous data indicate that the accumulation of AGEs in the extracellular matrix plays a key role in the development of obesity-re...
Echinacoside-Zinc Nanomaterial Inhibits Skin Glycation by Suppressing the Transcriptional Activation of the Receptor for Advanced Glycation End-Products.
Publication Type: Academic Journal
Source(s): ACS nano [ACS Nano] 2023 Jul 25; Vol. 17 (14), pp. 14123-14135. Date of Electronic Publication: 2023 Jul 05.
Abstract: Glycation is a nonenzymatically catalyzed spontaneous reaction that eventually leads to the formation of advanced glycation end-products (AGEs), which can bind to the receptor for AGEs (RAGE). The consequences are oxidative damage, an inflammatory resp...
RAGE pathways play an important role in regulation of organ fibrosis.
Publication Type: Academic Journal
Source(s): Life sciences [Life Sci] 2023 Jun 15; Vol. 323, pp. 121713. Date of Electronic Publication: 2023 Apr 23.
Abstract: Organ fibrosis is a pathological process of fibroblast activation and excessive deposition of extracellular matrix after persistent tissue injury and therefore is a common endpoint of many organ pathologies. Multiple cellular types and soluble mediator...
A Role for Advanced Glycation End Products in Molecular Ageing.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jun 08; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 08.
Abstract: Ageing is a composite process that involves numerous changes at the cellular, tissue, organ and whole-body levels. These changes result in decreased functioning of the organism and the development of certain conditions, which ultimately lead to an incr...
Impact of medium cut-off membranes on S100A12 and soluble receptor for advanced glycation end products.
Publication Type: Academic Journal
Source(s): Seminars in dialysis [Semin Dial] 2023 May-Jun; Vol. 36 (3), pp. 193-200. Date of Electronic Publication: 2022 Jun 10.
Abstract: Introduction: Of the most remarkable molecules associated with atherosclerosis and the cardiovascular outcome are S100A12 (10,379.5 Da) and soluble receptor for advanced glycation end products (sRAGE-42,803 Da) in the hemodialysis (HD) population. We d...