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Advanced Search Results For "SILICOSIS"

1 - 10 of 9,394 results for
 "SILICOSIS"
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Cyclophilin A accelerates SiO 2 -induced macrophage foaming.

Publication Type: Academic Journal

Source(s): Cellular signalling [Cell Signal] 2023 Mar; Vol. 103, pp. 110562. Date of Electronic Publication: 2022 Dec 16.

Authors:

Abstract: Silicosis is a common occupational disease characterized by lung inflammation, fibrosis and pulmonary dysfunction caused by long-term inhalation of free SiO 2 . Cell foaming and the change of CyPA have been observed in SiO 2 -induced macrophages, but t...

Lipid dysregulation associated with progression of silica-induced pulmonary fibrosis.

Publication Type: Academic Journal

Source(s): Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Feb 17; Vol. 191 (2), pp. 296-307.

Authors:

Abstract: Silicosis is an irreversible, progressive, fibrotic lung disease caused by long-term exposure to dust-containing silica particles at the workplace. Despite the precautions enforced, the rising incidence of silicosis continues to occur globally, particu...

Erasmus Syndrome: An Underrecognized Entity.

Publication Type: Academic Journal

Source(s): Acta medica portuguesa [Acta Med Port] 2023 Feb 01; Vol. 36 (2), pp. 122-126. Date of Electronic Publication: 2022 May 13.

Abstract: We present a case of a 33-year-old male who worked as a plumber and a locksmith. The patient presented with diffuse myalgia and asthenia, skin sclerosis and puffy fingers, Raynaud's phenomenon, exertional dyspnea and erectile dysfunction. The presence ...

Yangqing Chenfei formula attenuates silica-induced pulmonary fibrosis by suppressing activation of fibroblast via regulating PI3K/AKT, JAK/STAT, and Wnt signaling pathway.

Publication Type: Academic Journal

Source(s): Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Feb; Vol. 110, pp. 154622. Date of Electronic Publication: 2022 Dec 22.

Authors:

Abstract: Background: Yangqing Chenfei formula (YCF) has been demonstrated its clinical efficiency on silicosis patients. However, the effect of YCF against silicotic fibrosis and its mechanism remain unclear.Purpose: This study is aimed to investigate active co...

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles alleviated silica induced lung inflammation and fibrosis in mice via circPWWP2A/miR-223-3p/NLRP3 axis.

Publication Type: Academic Journal

Source(s): Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2023 Feb; Vol. 251, pp. 114537. Date of Electronic Publication: 2023 Jan 14.

Authors:

Abstract: Silicosis is a progressive inflammatory disease with poorly defined mechanisms and limited therapeutic options. Recent studies found that microRNAs (miRNAs) and circular RNAs (circRNAs) were involved in the development of respiratory diseases; however,...

Effects of Green Tea Polyphenol Epigallocatechin-3-Gallate on Markers of Inflammation and Fibrosis in a Rat Model of Pulmonary Silicosis.

Publication Type: Academic Journal

Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jan 17; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 17.

Abstract: Inhalation of silica particles causes inflammatory changes leading to fibrotizing silicosis. Considering a lack of effective therapy, and a growing information on the wide actions of green tea polyphenols, particularly epigallocatechin-3-gallate (EGCG)...

MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.

Publication Type: Academic Journal

Source(s): Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2023 Jan 01; Vol. 249, pp. 114392. Date of Electronic Publication: 2022 Dec 09.

Authors:

Abstract: Epithelial-mesenchymal transdifferentiation of alveolar type Ⅱ epithelial cells is a vital source of pulmonary myofibroblasts, and myofibroblasts formation is recognized as an important phase in the pathological process of silicosis. miR-30c-5p has bee...

A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway.

Publication Type: Academic Journal

Source(s): Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2023 Jan 01; Vol. 249, pp. 114410. Date of Electronic Publication: 2022 Dec 12.

Authors:

Abstract: Silicosis, a disease characterized by diffuse fibrosis of the lung tissue, is caused by long-term inhalation of free silica (SiO 2 ) dust in the occupational environment and is currently the most serious occupational diseases of pneumoconiosis. Several...

Using Nicotine in A Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition.

Publication Type: Academic Journal

Source(s): Journal of visualized experiments : JoVE [J Vis Exp] 2023 Mar 03 (193). Date of Electronic Publication: 2023 Mar 03.

Authors:

Abstract: Smoking and exposure to silica are common among occupational workers, and silica is more likely to injure the lungs of smokers than non-smokers. The role of nicotine, the primary addictive ingredient in cigarettes, in silicosis development is unclear. ...

Combined application of multiple biomarkers for early auxiliary diagnosis of silicosis.

Publication Type: Academic Journal

Source(s): Toxicology and industrial health [Toxicol Ind Health] 2023 Mar; Vol. 39 (3), pp. 138-145. Date of Electronic Publication: 2023 Feb 03.

Authors:

Abstract: Silicosis is an important industrial health problem for those workers exposed to silica. The present study aimed to investigate the sensitivity and specificity of combined detection of biomarkers in early auxiliary diagnosis of silicosis, the risk fact...

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