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Advanced Search Results For "STEM cells"

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 "STEM cells"
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Prognostic Analysis of Human Pluripotent Stem Cells Based on Their Morphological Portrait and Expression of Pluripotent Markers.

Publication Type: Academic Journal

Source(s): International journal of molecular sciences [Int J Mol Sci] 2022 Oct 26; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 26.

Abstract: The ability of human pluripotent stem cells for unlimited proliferation and self-renewal promotes their application in the fields of regenerative medicine. The morphological assessment of growing colonies and cells, as a non-invasive method, allows the...

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Autophagy and pluripotency: self-eating your way to eternal youth.

Publication Type: Academic Journal

Source(s): Trends in cell biology [Trends Cell Biol] 2022 Oct; Vol. 32 (10), pp. 868-882. Date of Electronic Publication: 2022 Apr 28.

Authors:

Abstract: Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while retaining the potential to differentiate into virtually all normal cell types in the adult animal. Due to these remarkable properties, PSCs not only provide a superb system to i...

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Embryonic stem cells-derived mesenchymal stem cells do not differentiate into ovarian cells but improve ovarian function in POF mice.

Publication Type: Academic Journal

Source(s): Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Dec 20; Vol. 635, pp. 92-98. Date of Electronic Publication: 2022 Oct 09.

Abstract: Premature ovarian failure (POF) is characterized by amenorrhea, hypoestrogenism, elevated gonadotropin levels, and infertility. Although some of previous studies reported that Mesenchymal stem cells (MSC) transplantation could rescue the ovary function...

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Impact of Diabetes Mellitus on the Potential of Autologous Stem Cells and Stem Cell-Derived Microvesicles to Repair the Ischemic Heart.

Publication Type: Academic Journal

Source(s): Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2022 Oct; Vol. 36 (5), pp. 933-949. Date of Electronic Publication: 2021 Jul 12.

Abstract: Ischemic heart disease remains the leading cause of morbidity and mortality worldwide. Despite the advances in medical management and catheter-based therapy, mortality remains high, as does the risk of developing heart failure. Regenerative therapies h...

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Umbilical cord blood as a hematopoietic stem cell source in transplantation for pediatric sickle cell disease: current challenges and strategies.

Publication Type: Academic Journal

Source(s): Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [Transfus Apher Sci] 2022 Oct; Vol. 61 (5), pp. 103554. Date of Electronic Publication: 2022 Aug 29.

Authors:

Abstract: Allogeneic hematopoietic stem cell transplant (HSCT) is the only established cure for sickle cell disease (SCD), a hemolytic disorder that arises due to a point mutation in the hemoglobin A gene. The result is an abnormal sickle hemoglobin (HbS) replac...

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Successful Mobilization of Autologous Hematopoietic Peripheral Blood Stem Cells after Salvage Chemotherapy in Patients with Low CD34 Blood Cell Counts.

Publication Type: Academic Journal

Source(s): Transplantation and cellular therapy [Transplant Cell Ther] 2022 Nov; Vol. 28 (11), pp. 754-759. Date of Electronic Publication: 2022 Aug 22.

Abstract: A major barrier for proceeding to autologous stem cell transplantation (ASCT) is an inability to mobilize and collect an adequate number of peripheral blood (PB) stem cells (PBSC) for the transplant graft. Plerixafor added to granulocyte colony stimula...

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IL3 Has a Detrimental Effect on Hematopoietic Stem Cell Self-Renewal in Transplantation Settings.

Publication Type: Academic Journal

Source(s): International journal of molecular sciences [Int J Mol Sci] 2022 Oct 22; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 22.

Abstract: The ex vivo expansion and maintenance of long-term hematopoietic stem cells (LT-HSC) is crucial for stem cell-based gene therapy. A combination of stem cell factor (SCF), thrombopoietin (TPO), FLT3 ligand (FLT3) and interleukin 3 (IL3) cytokines has be...

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Single-cell mass cytometry analysis reveals stem cell heterogeneity.

Publication Type: Academic Journal

Source(s): Methods (San Diego, Calif.) [Methods] 2022 Dec; Vol. 208, pp. 9-18. Date of Electronic Publication: 2022 Oct 10.

Abstract: Cellular heterogeneity is fundamental to both developmental differentiation and disease establishment. Recent advances in high-throughput single-cell technology have been rapidly revolutionizing the resolution of our understanding of development and di...

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S100A6 as a Constituent and Potential Marker of Adult and Cancer Stem Cells.

Publication Type: Academic Journal

Source(s): Stem cell reviews and reports [Stem Cell Rev Rep] 2022 Dec; Vol. 18 (8), pp. 2699-2708. Date of Electronic Publication: 2022 Jul 07.

Abstract: Adult or tissue stem cells are present in various tissues of the organism where they reside in a specific environment called the niche. Owing to their ability to generate a progeny that can proliferate and differentiate into specialized cell types, adu...

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Using Pluripotent Stem Cells to Understand Normal and Leukemic Hematopoietic Development.

Publication Type: Academic Journal

Source(s): Stem cells translational medicine [Stem Cells Transl Med] 2022 Nov 18; Vol. 11 (11), pp. 1123-1134.

Abstract: Several decades have passed since the generation of the first embryonic stem cell (ESC) lines both in mice and in humans. Since then, stem cell biologists have tried to understand their potential biological and clinical uses for their implementation in...

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