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Advanced Search Results For "VIRUSES"

1 - 10 of 988,461 results for
 "VIRUSES"
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Identification and characterization of key residues in Zika virus envelope protein for virus assembly and entry.

Publication Type: Academic Journal

Source(s): Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 1604-1620.

Authors:

Abstract: Zika virus (ZIKV), a family member in the Flavivirus genus, has re-emerged as a global public health concern. The envelope (E) proteins of flaviviruses play a dual role in viral assembly and entry. To identify the key residues of E in virus entry, we g...

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Antiviral Effect of Isoquercitrin against Influenza A Viral Infection via Modulating Hemagglutinin and Neuraminidase.

Publication Type: Academic Journal

Source(s): International journal of molecular sciences [Int J Mol Sci] 2022 Oct 28; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 28.

Authors:

Abstract: Isoquercitrin (IQC) is a component abundantly present in many plants and is known to have an anti-viral effect against various viruses. In this study, we demonstrate that IQC exhibits strong anti-influenza A virus infection, and its effect is closely r...

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XiaoEr LianHuaQinqGan alleviates viral pneumonia in mice infected by influenza A and respiratory syncytial viruses.

Publication Type: Academic Journal

Source(s): Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 2355-2366.

Authors:

Abstract: Context: Xiaoer lianhuaqinqgan (XELH), developed based on Lianhua Qingwen (LHQW) prescription, contains 13 traditional Chinese medicines. It has completed the investigational new drug application to treat respiratory viral infections in children in Chi...

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Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever.

Publication Type: Editorial & Opinion

Source(s): Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 1390-1393.

Abstract: Lassa fever (LF) is endemic to broad regions of West Africa. Infection with Lassa virus (LASV), the etiologic agent of LF, results in a spectrum of clinical signs in humans, including severe and lethal hemorrhagic disease. Person-to-person transmission...

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A Retrospective Study of Viral Molecular Prevalences in Cats in Southern Italy (Campania Region).

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Nov 21; Vol. 14 (11). Date of Electronic Publication: 2022 Nov 21.

Abstract: From 2019 to 2021, a retrospective molecular study was conducted in the Campania region (southern Italy) to determine the prevalence of viral diseases in domestic cats. A total of 328 dead animals were analyzed by Real-Time PCR for the presence of feli...

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Functional diversity: update of the posttranslational modification of Epstein-Barr virus coding proteins.

Publication Type: Academic Journal

Source(s): Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Nov 14; Vol. 79 (12), pp. 590. Date of Electronic Publication: 2022 Nov 14.

Authors:

Abstract: Epstein-Barr virus (EBV), a human oncogenic herpesvirus with a typical life cycle consisting of latent phase and lytic phase, is associated with many human diseases. EBV can express a variety of proteins that enable the virus to affect host cell proces...

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Phosphatidylinositol 4,5-Bisphosphate Mediates the Co-Distribution of Influenza A Hemagglutinin and Matrix Protein M1 at the Plasma Membrane.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Nov 12; Vol. 14 (11). Date of Electronic Publication: 2022 Nov 12.

Abstract: The fully assembled influenza A virus (IAV) has on its surface the highest density of a single membrane protein found in nature-the glycoprotein hemagglutinin (HA) that mediates viral binding, entry, and assembly. HA clusters at the plasma membrane of ...

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Levels of Influenza A Virus Defective Viral Genomes Determine Pathogenesis in the BALB/c Mouse Model.

Publication Type: Academic Journal

Source(s): Journal of virology [J Virol] 2022 Nov 09; Vol. 96 (21), pp. e0117822. Date of Electronic Publication: 2022 Oct 13.

Abstract: Defective viral genomes (DVGs), which are generated by the viral polymerase in error during RNA replication, can trigger innate immunity and are implicated in altering the clinical outcome of infection. Here, we investigated the impact of DVGs on innat...

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Improving Statistical Certainty of Glycosylation Similarity between Influenza A Virus Variants Using Data-Independent Acquisition Mass Spectrometry.

Publication Type: Academic Journal

Source(s): Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2022 Nov; Vol. 21 (11), pp. 100412. Date of Electronic Publication: 2022 Sep 11.

Abstract: Amino acid sequences of immunodominant domains of hemagglutinin (HA) on the surface of influenza A virus (IAV) evolve rapidly, producing viral variants. HA mediates receptor recognition, binding and cell entry, and serves as the target for IAV vaccines...

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Decoding the Role of Temperature in RNA Virus Infections.

Publication Type: Academic Journal

Source(s): MBio [mBio] 2022 Oct 26; Vol. 13 (5), pp. e0202122. Date of Electronic Publication: 2022 Aug 18.

Abstract: RNA viruses include respiratory viruses, such as coronaviruses and influenza viruses, as well as vector-borne viruses, like dengue and West Nile virus. RNA viruses like these encounter various environments when they copy themselves and spread from cell...

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