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Cluster headache polygenetic risk and known functional variants of CYP3A4 are not associated with treatment response.
Publication Type: Academic Journal
Source(s): European journal of neurology [Eur J Neurol] 2023 May; Vol. 30 (5), pp. 1425-1434. Date of Electronic Publication: 2023 Mar 02.
Abstract: Background and Purpose: The response to cluster headache treatments has a high interindividual variation. To date, treatment response has only been assessed by a candidate gene approach and no investigations into metabolic pathways have been performed....
COVID-19 vaccination elicited de novo and recurrence of cluster headache: A case series.
Publication Type: Academic Journal
Source(s): Cephalalgia : an international journal of headache [Cephalalgia] 2023 May; Vol. 43 (5), pp. 3331024231173354.
Abstract: Background: Recent pharmacovigilance studies suggested that cluster headache could be a potential adverse effect after coronavirus disease-2019 (COVID-19) vaccination; however, the possibility of coincidence could not be excluded. Detailed case studies...
Cluster headache and kynurenines.
Publication Type: Academic Journal
Source(s): The journal of headache and pain [J Headache Pain] 2023 Apr 05; Vol. 24 (1), pp. 35. Date of Electronic Publication: 2023 Apr 05.
Abstract: Background: The glutamatergic neurotransmission has important role in the pathomechanism of primary headache disorders. The kynurenine metabolites derived from catabolism of tryptophan (Trp) have significant involvement not only in glutamatergic proces...
Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers.
Publication Type: Academic Journal
Source(s): Cephalalgia : an international journal of headache [Cephalalgia] 2023 Apr; Vol. 43 (4), pp. 3331024231161269.
Abstract: Objective: Inhalation of oxygen is highly effective in cluster headache, a subtype of trigeminal autonomic cephalgias. Since oxygen has no effect on nociceptive pain, the mechanism of action is still unknown. The present study investigated whether oxyg...
Sex Differences in Clinical Features, Treatment, and Lifestyle Factors in Patients With Cluster Headache.
Publication Type: Academic Journal
Source(s): Neurology [Neurology] 2023 Mar 21; Vol. 100 (12), pp. e1207-e1220. Date of Electronic Publication: 2022 Dec 21.
Abstract: Background and Objectives: Cluster headache is considered a male-dominated disorder, but we have previously suggested that female patients may display a more severe phenotype. Studies on sex differences in cluster headache have been conflicting; theref...
Imaging the brain and vascular reactions to headache treatments: a systematic review.
Publication Type: Academic Journal
Source(s): The journal of headache and pain [J Headache Pain] 2023 May 24; Vol. 24 (1), pp. 58. Date of Electronic Publication: 2023 May 24.
Abstract: Background: Neuroimaging studies have made an important contribution to our understanding of headache pathophysiology. This systematic review aims to provide a comprehensive overview and critical appraisal of mechanisms of actions of headache treatment...
Verification of a clinical decision support system for the diagnosis of headache disorders based on patient-computer interactions: a multi-center study.
Publication Type: Academic Journal
Source(s): The journal of headache and pain [J Headache Pain] 2023 May 23; Vol. 24 (1), pp. 57. Date of Electronic Publication: 2023 May 23.
Abstract: Background: Although headache disorders are common, the current diagnostic approach is unsatisfactory. Previously, we designed a guideline-based clinical decision support system (CDSS 1.0) for diagnosing headache disorders. However, the system requires...
Developing prediction models when there are systematically missing predictors in individual patient data meta-analysis.
Publication Type: Academic Journal
Source(s): Research synthesis methods [Res Synth Methods] 2023 May; Vol. 14 (3), pp. 455-467. Date of Electronic Publication: 2023 Feb 23.
Abstract: Clinical prediction models are widely used in modern clinical practice. Such models are often developed using individual patient data (IPD) from a single study, but often there are IPD available from multiple studies. This allows using meta-analytical ...
Cytokines in primary headache disorders: a systematic review and meta-analysis.
Publication Type: Academic Journal
Source(s): The journal of headache and pain [J Headache Pain] 2023 Apr 04; Vol. 24 (1), pp. 36. Date of Electronic Publication: 2023 Apr 04.
Abstract: Background: The role of inflammation and cytokines in the pathophysiology of primary headache disorders is uncertain. We performed a systematic review and meta-analysis to synthesise the results of studies comparing peripheral blood cytokine levels bet...
Are psychedelics the answer to chronic pain: A review of current literature.
Publication Type: Academic Journal
Source(s): Pain practice : the official journal of World Institute of Pain [Pain Pract] 2023 Apr; Vol. 23 (4), pp. 447-458. Date of Electronic Publication: 2023 Jan 11.
Abstract: Aims: We aim to provide an evidence-based overview of the use of psychedelics in chronic pain, specifically LSD and psilocybin.Content: Chronic pain is a common and complex problem, with an unknown etiology. Psychedelics like lysergic acid diethylamide...