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Advanced Search Results For "coronavirus"

1 - 10 of 125,378 results for
 "coronavirus"
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Coronaviruses exploit a host cysteine-aspartic protease for replication.

Publication Type:Academic Journal

Source(s):Nature [Nature] 2022 Sep; Vol. 609 (7928), pp. 785-792. Date of Electronic Publication: 2022 Aug 03.

Abstract:Highly pathogenic coronaviruses, including severe acute respiratory syndrome coronavirus 2 (refs.  1,2 ) (SARS-CoV-2), Middle East respiratory syndrome coronavirus 3 (MERS-CoV) and SARS-CoV-1 (ref.  4 ), vary in their transmissibility and pathogenicity...

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Human coronaviruses: Origin, host and receptor.

Publication Type:Academic Journal

Source(s):Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [J Clin Virol] 2022 Oct; Vol. 155, pp. 105246. Date of Electronic Publication: 2022 Jul 21.

Abstract:Coronavirus is a type of RNA-positive single-stranded virus with an envelope, and the spines on its surface derived its official name. Seven human coronaviruses 229E, OC43, SARS, NL63, HKU1, MERS, SARS-CoV-2 can cause both a mild cold and an epidemic o...

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Pan-coronavirus epitope buried in spike.

Publication Type:Academic Journal

Source(s):Nature reviews. Microbiology [Nat Rev Microbiol] 2022 Sep; Vol. 20 (9), pp. 510.

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PEDV: Insights and Advances into Types, Function, Structure, and Receptor Recognition.

Publication Type:Academic Journal

Source(s):Viruses [Viruses] 2022 Aug 09; Vol. 14 (8). Date of Electronic Publication: 2022 Aug 09.

Abstract:Porcine epidemic diarrhea virus (PEDV) has been endemic in most parts of the world since its emergence in the 1970s. It infects the small intestine and intestinal villous cells, spreads rapidly, and causes infectious intestinal disease characterized by...

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Human seasonal coronavirus neutralization and COVID-19 severity.

Publication Type:Academic Journal

Source(s):Journal of medical virology [J Med Virol] 2022 Oct; Vol. 94 (10), pp. 4820-4829. Date of Electronic Publication: 2022 Jul 18.

Abstract:The virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the global coronavirus disease-2019 (COVID-19) pandemic, spread rapidly around the world causing high morbidity and mortality. However, there are four known, endemi...

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Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor.

Publication Type:Academic Journal

Source(s):Viruses [Viruses] 2022 Sep 18; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 18.

Abstract:The ongoing spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused hundreds of millions of cases and millions of victims worldwide with serious consequences to global health and economies. Although many vaccines protecting ag...

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Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species.

Publication Type:Academic Journal

Source(s):Cell reports [Cell Rep] 2022 Aug 02; Vol. 40 (5), pp. 111160. Date of Electronic Publication: 2022 Jul 19.

Abstract:Although COVID-19 vaccines have been developed, multiple pathogenic coronavirus species exist, urging on development of multispecies coronavirus vaccines. Here we develop prototype lipid nanoparticle (LNP)-mRNA vaccine candidates against SARS-CoV-2 Del...

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Transchromosomic bovines-derived broadly neutralizing antibodies as potent biotherapeutics to counter important emerging viral pathogens with a special focus on SARS-CoV-2, MERS-CoV, Ebola, Zika, HIV-1, and influenza A virus.

Publication Type:Academic Journal

Source(s):Journal of medical virology [J Med Virol] 2022 Oct; Vol. 94 (10), pp. 4599-4610. Date of Electronic Publication: 2022 Jun 11.

Abstract:Historically, passive immunotherapy is an approved approach for protecting and treating humans against various diseases when other alternative therapeutic options are unavailable. Human polyclonal antibodies (hpAbs) can be made from convalescent human ...

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SARS-CoV-2 Seroprevalence Study in Pediatric Patients and Health Care Workers Using Multiplex Antibody Immunoassays.

Publication Type:Academic Journal

Source(s):Viruses [Viruses] 2022 Sep 14; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 14.

Abstract:SARS-CoV-2 infection has become a global health problem specially exacerbated with the continuous appearance of new variants. Healthcare workers (HCW) have been one of the most affected sectors. Children have also been affected, and although infection ...

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RG203KR Mutations in SARS-CoV-2 Nucleocapsid: Assessing the Impact Using a Virus-Like Particle Model System.

Publication Type:Academic Journal

Source(s):Microbiology spectrum [Microbiol Spectr] 2022 Aug 31; Vol. 10 (4), pp. e0078122. Date of Electronic Publication: 2022 Jul 06.

Abstract:The emergence and evolution of SARS-CoV-2 is characterized by the occurrence of diverse sets of mutations that affect virus characteristics, including transmissibility and antigenicity. Recent studies have focused mostly on spike protein mutations; how...

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