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Advanced Search Results For "drug delivery"

1 - 10 of 214,661 results for
 "drug delivery"
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Nano drug delivery systems for antisense oligonucleotides (ASO) therapeutics.

Publication Type: Academic Journal

Source(s): Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2022 Dec; Vol. 352, pp. 861-878. Date of Electronic Publication: 2022 Nov 14.

Abstract: Cancer, infectious diseases, and metabolic and hereditary genetic disorders are a global health burden affecting millions of people, with contemporary treatments offering limited relief. Antisense technology treats diseases by targeting their causal ag...

Effect of Lipophilic Chains on the Antitumor Effect of a Dendritic Nano Drug Delivery System.

Publication Type: Academic Journal

Source(s): Molecules (Basel, Switzerland) [Molecules] 2022 Dec 21; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 21.

Authors:

Abstract: Oligoethylene glycol dendron (G2) has been used in drug delivery due to its unique dendritic structure and excellent properties. In order to investigate the effects of lipophilic chains on drug delivery, the amphiphilic hybrid compound G2-C18 is synthe...

Preparation of topical bimatoprost with enhanced skin infiltration and in vivo hair regrowth efficacy in androgenic alopecia.

Publication Type: Academic Journal

Source(s): Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 328-341.

Abstract: To prepare a topical formulation of bimatoprost (BIM) with high skin permeability, we designed a solvent mixture system composed of ethanol, diethylene glycol monoethyl ether, cyclomethicone, and butylated hydroxyanisole, serving as a volatile solvent,...

User-designed device with programmable release profile for localized treatment.

Publication Type: Academic Journal

Source(s): Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2022 Dec; Vol. 352, pp. 685-699. Date of Electronic Publication: 2022 Nov 09.

Authors:

Abstract: Three-dimensional printing enables precise and on-demand manufacture of customizable drug delivery systems to advance healthcare toward the goal of personalized medicine. However, major challenges remain in realizing personalized drug delivery that fit...

Nano-enabled plant-based colloidal delivery systems for bioactive agents in foods: Design, formulation, and application.

Publication Type: Academic Journal

Source(s): Advances in colloid and interface science [Adv Colloid Interface Sci] 2022 Jul; Vol. 305, pp. 102709. Date of Electronic Publication: 2022 May 26.

Abstract: Consumers are becoming increasingly aware of the impact of their dietary choices on the environment, animal welfare, and health, which is causing many of them to adopt more plant-based diets. For this reason, many sectors of the food industry are refor...

Ocular barriers as a double-edged sword: preventing and facilitating drug delivery to the retina.

Publication Type: Academic Journal

Source(s): Drug delivery and translational research [Drug Deliv Transl Res] 2023 Feb; Vol. 13 (2), pp. 547-567. Date of Electronic Publication: 2022 Sep 21.

Authors:

Abstract: In recent decades, the growing of the aging population in the world brings increasingly heavy burden of vision-threatening retinal diseases. One of the biggest challenges in the treatment of retinal diseases is the effective drug delivery to the diseas...

Lymphatic targeting for therapeutic application using nanoparticulate systems.

Publication Type: Academic Journal

Source(s): Journal of drug targeting [J Drug Target] 2022 Dec; Vol. 30 (10), pp. 1017-1033. Date of Electronic Publication: 2022 Jul 04.

Abstract: The lymphatic system has grasped attention of researchers to a greater extent. The conventional methods of lymphatic delivery are now being modified to include nanotechnology to enhance the targeting of the drug at the specific pathological site. Scien...

Flexible nano-liposomes-based transdermal hydrogel for targeted delivery of dexamethasone for rheumatoid arthritis therapy.

Publication Type: Academic Journal

Source(s): Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 2269-2282.

Abstract: Rheumatoid arthritis (RA) is an inflammatory immune-mediated disease that can lead to synovitis, cartilage destruction, and even joint damage. Dexamethasone (DEX) is a commonly used agent for RA therapy on inflammation manage. However, the traditional ...

Shear induced fractionalized dispersion during Magnetic Drug Targeting in a permeable microvessel.

Publication Type: Academic Journal

Source(s): Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2023 Jan; Vol. 221, pp. 113001. Date of Electronic Publication: 2022 Nov 03.

Abstract: Solute dispersion is a significant phenomenon during drug targeting to estimate the accumulation of drug particles at the tumour region with the capture efficiency. In this present study, we aim to predict the effective dispersion and saturated concent...

Enhanced stability and oral bioavailability of erlotinib by solid self nano emulsifying drug delivery systems.

Publication Type: Academic Journal

Source(s): International journal of pharmaceutics [Int J Pharm] 2022 Jun 25; Vol. 622, pp. 121852. Date of Electronic Publication: 2022 May 23.

Abstract: The present investigation demonstrates the preparation of solid self nanoemulsfying drug delivery system (sSNEDDS) to enhance stability and bioavailability of Erlotinib (ERL) via the oral route. Capmul®MCM EP (CPM EP, oil), Cremophor® RH 40 (CMR RH 40,...

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