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Early Postoperative Volume Overload is a Predictor of 1-Year Post-Transplant Mortality in Pediatric Heart Transplant Recipients.
Publication Type: Academic Journal
Source(s): Pediatric cardiology [Pediatr Cardiol] 2023 Jun; Vol. 44 (5), pp. 1014-1022. Date of Electronic Publication: 2023 Mar 22.
Abstract: Fluid restriction and diuretic management are mainstays in the postoperative management of cardiac patients, at risk of volume overload and its deleterious effects on primary cardiac function and multi-organ systems. The importance of fluid homeostasis...
Clinical approach to antibody-mediated rejection from the pediatric heart transplant society.
Publication Type: Academic Journal
Source(s): Pediatric transplantation [Pediatr Transplant] 2022 Dec; Vol. 26 (8), pp. e14398.
Abstract: Objective: This document is designed to outline the definition, pathogenesis, diagnostic modalities and therapeutic measures to treat antibody-mediated rejection in children postheart transplant METHODS: Literature review was conducted by a Pediatric H...
Adaptation of a population pharmacokinetic model to inform tacrolimus therapy in heart transplant recipients.
Publication Type: Academic Journal
Source(s): British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Mar; Vol. 89 (3), pp. 1162-1175. Date of Electronic Publication: 2022 Nov 06.
Abstract: Aim: Existing tacrolimus population pharmacokinetic models are unsuitable for guiding tacrolimus dosing in heart transplant recipients. This study aimed to develop and evaluate a population pharmacokinetic model for tacrolimus in heart transplant recip...
Development of donor specific antibodies after SARS-CoV-2 vaccination in kidney and heart transplant recipients.
Publication Type: Academic Journal
Source(s): Transplant immunology [Transpl Immunol] 2022 Dec; Vol. 75, pp. 101722. Date of Electronic Publication: 2022 Sep 22.
Abstract: This study examined the development of new or changes in donor specific antibodies (DSA) mean-fluorescence intensity (MFI) after SARS-CoV-2 vaccination in 100 kidney and 50 heart transplant recipients. The study was performed when the Center for Diseas...
Impact of the United Network for Organ Sharing policy change on induction immunosuppression practice patterns and outcomes in adult heart transplant recipients.
Publication Type: Academic Journal
Source(s): Pharmacotherapy [Pharmacotherapy] 2023 Feb; Vol. 43 (2), pp. 115-121. Date of Electronic Publication: 2023 Jan 09.
Abstract: Objective: We evaluated whether the new allocation system altered induction practice patterns and affected outcomes in adult HT recipients.Design: Retrospective, observational, cohort study.Data Source: This study used data from the United Network for ...
Immune cell function assay and T lymphocyte counts lack association with rejection or infection in pediatric heart transplant recipients.
Publication Type: Academic Journal
Source(s): Clinical transplantation [Clin Transplant] 2023 Feb; Vol. 37 (2), pp. e14858. Date of Electronic Publication: 2022 Nov 27.
Abstract: Introduction: Immune cell function assay (ICFA) and CD3 lymphocyte counts have been considered to be useful in discerning the overall intensity of immunosuppression in pediatric orthotopic heart transplant (OHT) recipients.Methods: The aim of this retr...
Risks of paxlovid in a heart transplant recipient.
Publication Type: Academic Journal
Source(s): The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2023 Jan; Vol. 42 (1), pp. 30-32. Date of Electronic Publication: 2022 Sep 08.
Abstract: The burden of morbidity and mortality from SARS-CoV-2 infection is especially significant in heart transplant patients who are at higher risk for poor outcomes owing to immunosuppression, blunted response to vaccination, and multiple comorbid condition...
Retrospective analysis of the impact of pre-transplant implantable cardioverter-defibrillator status on long-term prognosis in heart transplant patients.
Publication Type: Academic Journal
Source(s): Clinical transplantation [Clin Transplant] 2023 Jan; Vol. 37 (1), pp. e14842. Date of Electronic Publication: 2022 Nov 27.
Abstract: Background: Sudden cardiac death (SCD) post-heart transplantation affects 8%-35% of patients; however, the risk profile remains to be completely elucidated. While pre-transplant ICDs are typically removed during transplantation, no information exists t...
Low acceptance rate of COVID-19 vaccination and reduced quality of life among heart transplant recipients during the COVID-19 pandemic.
Publication Type: Academic Journal
Source(s): Journal of cardiac surgery [J Card Surg] 2022 Dec; Vol. 37 (12), pp. 4975-4981. Date of Electronic Publication: 2022 Nov 29.
Abstract: Objectives: To investigate the impact of the current coronavirus disease 2019 (COVID-19) pandemic on the quality of life (QoL) and status of COVID-19 vaccination in heart transplant recipients (HTRs).Methods: Patients who underwent allogeneic heart tra...
COVID-19 in orthotopic heart transplant recipients and association with donor specific antibodies.
Publication Type: Academic Journal
Source(s): Transplant immunology [Transpl Immunol] 2022 Dec; Vol. 75, pp. 101712. Date of Electronic Publication: 2022 Sep 11.
Abstract: De novo donor-specific antibodies (DSAs) are associated with increased risk of antibody-mediated rejection and worse clinical outcomes after orthotopic heart transplant (OHT). No study has reported the production of DSAs after infection by Severe Acute...