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Alternative lengthening of telomeres in primary hepatic neoplasms.
Publication Type: Academic Journal
Source(s): Human pathology [Hum Pathol] 2023 Jan; Vol. 131, pp. 79-86. Date of Electronic Publication: 2022 Nov 09.
Abstract: The alternative lengthening of telomeres (ALT) phenotype is characterized by ultra-bright telomeres on fluorescence in situ hybridization (FISH) and is a marker of a unique mechanism of telomere maintenance in tumors. ALT does not occur in normal tissu...
Different 18F-FDG imaging: A rare case of liver multiple carcinomas.
Publication Type: Academic Journal
Source(s): Clinics and research in hepatology and gastroenterology [Clin Res Hepatol Gastroenterol] 2023 Jan; Vol. 47 (1), pp. 102050. Date of Electronic Publication: 2022 Nov 12.
Abstract: A 49-year-old man was referred to the hospital with the complaints of haematochezia and weight loss. Colonoscopy and pathological needle biopsy suggested moderately to highly differentiated adenocarcinoma. The patient underwent abdominal CT examination...
MRI appearance of combined hepatocellular cholangiocarcinoma.
Publication Type: Academic Journal
Source(s): Diagnostic and interventional imaging [Diagn Interv Imaging] 2022 Dec; Vol. 103 (12), pp. 625-626. Date of Electronic Publication: 2022 Oct 13.
Abstract: Competing Interests: Declaration of Competing Interests The authors declare that they have no competing interest.
Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH).
Publication Type: Academic Journal
Source(s): Gastroenterologia y hepatologia [Gastroenterol Hepatol] 2022 Nov; Vol. 45 (9), pp. 724-734. Date of Electronic Publication: 2022 Mar 03.
Abstract: This is a meeting report of the 3rd Translational Hepatology Meeting held in Alicante, Spain, in October 2021. The meeting, which was organized by the Spanish Association for the Study of the Liver (AEEH), provided an update on the recent advances in t...
Benefits of combination therapy with immune checkpoint inhibitors and predictive role of tumour mutation burden in hepatocellular carcinoma: A systematic review and meta-analysis.
Publication Type: Academic Journal
Source(s): International immunopharmacology [Int Immunopharmacol] 2022 Nov; Vol. 112, pp. 109244. Date of Electronic Publication: 2022 Sep 18.
Abstract: Objectives: To investigate the clinical benefits of combination therapy with immune checkpoint inhibitors (ICIs) and best combination regimen for people with advanced hepatocellular carcinoma (HCC) and to explore the predictive performance of tumour mu...
A functional variant in the RAD51 3' UTR is associated with survival of hepatocellular carcinoma patients.
Publication Type: Academic Journal
Source(s): Gene [Gene] 2023 Jan 30; Vol. 851, pp. 146964. Date of Electronic Publication: 2022 Oct 17.
Abstract: The RAD51 gene plays an important role in DNA repair by homologous recombination, and is involved in the development and progression of multiple cancers. Single nucleotide polymorphisms in RAD51 have been previously described to impact the prognosis of...
Huaier granule prolongs overall survival after curative resection of hepatocarcinoma carcinoma: A propensity score analysis.
Publication Type: Academic Journal
Source(s): Journal of ethnopharmacology [J Ethnopharmacol] 2023 Jan 30; Vol. 301, pp. 115774. Date of Electronic Publication: 2022 Oct 04.
Abstract: Background: The effectiveness and safety of huaier granules in reducing recurrence after curative resection of HCC have been confirmed, but it is unclear whether huaier granules can significantly prolong overall survival.Aim: To demonstrate the effecti...
Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet.
Publication Type: Academic Journal
Source(s): BMC cancer [BMC Cancer] 2023 Jan 17; Vol. 23 (1), pp. 59. Date of Electronic Publication: 2023 Jan 17.
Abstract: Background: Saroglitazar is a novel PPAR-α/γ agonist with predominant PPAR-α activity. In various preclinical models, saroglitazar has been shown to prevent & reverse symptoms of NASH. In view of these observations, and the fact that NASH is a progress...
Construction and verification of a novel circadian clock related long non-coding RNA model and prediction of treatment for survival prognosis in patients with hepatocellular carcinoma.
Publication Type: Academic Journal
Source(s): BMC cancer [BMC Cancer] 2023 Jan 17; Vol. 23 (1), pp. 57. Date of Electronic Publication: 2023 Jan 17.
Abstract: Circadian clock genes are significant in the occurrence and development of HCC and long-non coding RNAs (lncRNAs) are closely related to HCC progression. In this study, we aimed to establish a prognostic risk model for HCC. Circadian clock-related lncR...
Circulating Bile Acids as Biomarkers for Disease Diagnosis and Prevention.
Publication Type: Academic Journal
Source(s): The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2023 Jan 17; Vol. 108 (2), pp. 251-270.
Abstract: Context: Bile acids (BAs) are pivotal signaling molecules that regulate energy metabolism and inflammation. Recent epidemiological studies have reported specific alterations in circulating BA profiles in certain disease states, including obesity, type ...