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Advanced Search Results For "inter-"

1 - 10 of 181 results for
 "inter-"
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Maize Introgression Library Provides Evidence for the Involvement of liguleless1 in Resistance to Northern Leaf Blight

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3611-3622 (2020)

Abstract:Plant disease resistance is largely governed by complex genetic architecture. In maize, few disease resistance loci have been characterized. Near-isogenic lines are a powerful genetic tool to dissect quantitative trait loci. We analyzed an introgressio...

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A Nested Association Mapping Panel in Arabidopsis thaliana for Mapping and Characterizing Genetic Architecture

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3701-3708 (2020)

Abstract:Linkage and association mapping populations are crucial public resources that facilitate the characterization of trait genetic architecture in natural and agricultural systems. We define a large nested association mapping panel (NAM) from 14 publicly a...

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Antipsychotic Behavioral Phenotypes in the Mouse Collaborative Cross Recombinant Inbred Inter-Crosses (RIX)

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3165-3177 (2020)

Abstract:Schizophrenia is an idiopathic disorder that affects approximately 1% of the human population, and presents with persistent delusions, hallucinations, and disorganized behaviors. Antipsychotics are the standard pharmacological treatment for schizophren...

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Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 10, Iss 7, Pp 2529-2541 (2020)

Abstract:Plasma concentration of Cystatin C (CysC) level is a biomarker of glomerular filtration rate in the kidney. We use a Systems Genetics approach to investigate the genetic determinants of plasma CysC concentration. To do so we perform Quantitative Trait ...

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Genome-Wide Association Study in Two Cohorts from a Multi-generational Mouse Advanced Intercross Line Highlights the Difficulty of Replication Due to Study-Specific Heterogeneity

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 10, Iss 3, Pp 951-965 (2020)

Abstract:There has been extensive discussion of the “Replication Crisis” in many fields, including genome-wide association studies (GWAS). We explored replication in a mouse model using an advanced intercross line (AIL), which is a multigenerational intercross ...

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Partner Choice in Spontaneous Mitotic Recombination in Wild Type and Homologous Recombination Mutants of Candida albicans

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3631-3644 (2019)

Abstract:Candida albicans, the most common fungal pathogen, is a diploid with a genome that is rich in repeats and has high levels of heterozygosity. To study the role of different recombination pathways on direct-repeat recombination, we replaced either allele...

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Testing Pleiotropy vs. Separate QTL in Multiparental Populations

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2317-2324 (2019)

Abstract:The high mapping resolution of multiparental populations, combined with technology to measure tens of thousands of phenotypes, presents a need for quantitative methods to enhance understanding of the genetic architecture of complex traits. When multipl...

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Genetic Dissection of Resistance to the Three Fungal Plant Pathogens Blumeria graminis, Zymoseptoria tritici, and Pyrenophora tritici-repentis Using a Multiparental Winter Wheat Population

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1745-1757 (2019)

Abstract:Bread wheat (Triticum aestivum L.) is one of the world’s most important crop species. The development of new varieties resistant to multiple pathogens is an ongoing task in wheat breeding, especially in times of increasing demand for sustainable agricu...

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A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1613-1622 (2019)

Abstract:Reproductive success in the eight founder strains of the Collaborative Cross (CC) was measured using a diallel-mating scheme. Over a 48-month period we generated 4,448 litters, and provided 24,782 weaned pups for use in 16 different published experimen...

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Determinants of QTL Mapping Power in the Realized Collaborative Cross

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1707-1727 (2019)

Abstract:The Collaborative Cross (CC) is a mouse genetic reference population whose range of applications includes quantitative trait loci (QTL) mapping. The design of a CC QTL mapping study involves multiple decisions, including which and how many strains to u...

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