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Permeability determination and pharmacokinetic study of nobiletin in rat plasma and brain by validated high-performance liquid chromatography method

Publication Type: Academic Journal

Source(s): Fitoterapia. Dec2011, Vol. 82 Issue 8, p1206-1214. 9p.

Abstract: Abstract: In the present study, we are reporting permeability and pharmacokinetics of nobiletin in rat plasma and brain, using a validated reverse phase high performance liquid chromatographic method. Protein precipitation method was used for the extra...