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  • Subject: protein array analysis
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    • Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

    Publication Type: Academic Journal

    Source(s): Archives of toxicology [Arch Toxicol] 2016 Sep; Vol. 90 (9), pp. 2215-2229. Date of Electronic Publication: 2015 Nov 02.

    Abstract: The assessment of the carcinogenic potential of chemicals with alternative, human-based in vitro systems has become a major goal of toxicogenomics. The central read-out of these assays is the transcriptome, and while many studies exist that explored th...

    Intravenous administration of silver nanoparticles causes organ toxicity through intracellular ROS-related loss of inter-endothelial junction.

    Publication Type: Academic Journal

    Source(s): Particle and fibre toxicology [Part Fibre Toxicol] 2016 Apr 29; Vol. 13, pp. 21. Date of Electronic Publication: 2016 Apr 29.

    Abstract: Background: Administration of silver nanoparticles (AgNPs) to mice could result in their distribution and accumulation in multiple organs, with notable prominence in liver, lungs, and kidneys. However, how AgNPs transport through blood vesicular system...

    Ecotoxicogenomics: Microarray interlaboratory comparability.

    Publication Type: Academic Journal

    Source(s): Chemosphere [Chemosphere] 2016 Feb; Vol. 144, pp. 193-200. Date of Electronic Publication: 2015 Sep 10.

    Abstract: Transcriptomic analysis can complement traditional ecotoxicology data by providing mechanistic insight, and by identifying sub-lethal organismal responses and contaminant classes underlying observed toxicity. Before transcriptomic information can be us...

    Direct role of interrod spacing in mediating cell adhesion on Sr-HA nanorod-patterned coatings.

    Publication Type: Academic Journal

    Source(s): International journal of nanomedicine [Int J Nanomedicine] 2014 Mar 08; Vol. 9, pp. 1243-60. Date of Electronic Publication: 2014 Mar 08 (Print Publication: 2014).

    Authors:

    Abstract: The process in which nanostructured surfaces mediate cell adhesion is not well understood, and may be indirect (via protein adsorption) or direct. We prepared Sr-doped hydroxyapatite (Sr1-HA) 3D nanorods (with interrod spacing of 67.3 ± 3.8, 95.7 ± 4.2...

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