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Advanced Search Results For "klebsiella pneumoniae"

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 "klebsiella pneumoniae"
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Anti-restriction protein ArdA promotes clinical Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae spread and its molecular mechanism.

Publication Type: Academic Journal

Source(s): The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2023 Feb 01; Vol. 78 (2), pp. 521-530.

Authors:

Abstract: Background: Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) has spread worldwide and has become a major threat to public health. The restriction modification system provides an innate defence of bacteria against plasmids or t...

Klebsiella Species and Enterobacter cloacae Isolates Harboring bla OXA-181 and bla OXA-48 : Resistome, Fitness Cost, and Plasmid Stability.

Publication Type: Academic Journal

Source(s): Microbiology spectrum [Microbiol Spectr] 2022 Dec 21; Vol. 10 (6), pp. e0332022. Date of Electronic Publication: 2022 Dec 01.

Authors:

Abstract: IncX3 and IncL plasmids have been named as catalysts advancing dissemination of bla OXA-181 and bla OXA-48 -containing Klebsiella pneumoniae (EFN299), Klebsiella quasipneumoniae (EFN262), and Enterobacter cloacae (EFN743) isolated from ...

Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure.

Publication Type: Academic Journal

Source(s): Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Sep 20; Vol. 119 (38), pp. e2203593119. Date of Electronic Publication: 2022 Sep 12.

Abstract: Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In Klebsiella pneumoniae , modifications in the porin OmpK36 are implicated in increasing resistance to carbapenems. An analysis of large K. pneumoniae genome collections, en...

Antibiotic resistance surveillance of Klebsiella pneumoniae complex is affected by refined MALDI-TOF identification, Swiss data, 2017 to 2022.

Publication Type: Academic Journal

Source(s): Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2022 Nov; Vol. 27 (45).

Abstract: BackgroundModern laboratory methods such as next generation sequencing and MALDI-TOF allow identification of novel bacterial species. This can affect surveillance of infections and antimicrobial resistance. From 2017, increasing numbers of medical micr...

Mechanistic Insights to Combating NDM- and CTX-M-Coproducing Klebsiella pneumoniae by Targeting Cell Wall Synthesis and Outer Membrane Integrity.

Publication Type: Academic Journal

Source(s): Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Sep 20; Vol. 66 (9), pp. e0052722. Date of Electronic Publication: 2022 Aug 04.

Abstract: Metallo-β-lactamase (MBL)-producing Gram-negative bacteria cause infections associated with high rates of morbidity and mortality. Currently, a leading regimen to treat infections caused by MBL-producing bacteria is aztreonam combined with ceftazidime-...

Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview.

Publication Type: Academic Journal

Source(s): Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Sep 20; Vol. 66 (9), pp. e0044722. Date of Electronic Publication: 2022 Aug 18.

Abstract: First variants of the Klebsiella pneumoniae carbapenemase (KPC), KPC-2 and KPC-3, have encountered a worldwide success, particularly in K. pneumoniae isolates. These beta-lactamases conferred resistance to most beta-lactams including carbapenems but re...

Diversity of lytic bacteriophages against XDR Klebsiella pneumoniae sequence type 16 recovered from sewage samples in different parts of the world.

Publication Type: Academic Journal

Source(s): The Science of the total environment [Sci Total Environ] 2022 Sep 15; Vol. 839, pp. 156074. Date of Electronic Publication: 2022 May 24.

Abstract: Bacteriophages (phages) are viruses considered to be natural bacterial predators and widely detected in aquatic environments. Sewage samples are an important source of phage isolation since high density and diversity of bacterial cells are present, due...

Molecular Characteristics of an NDM-4 and OXA-181 Co-Producing K51-ST16 Carbapenem-Resistant Klebsiella pneumoniae: Study of Its Potential Dissemination Mediated by Conjugative Plasmids and Insertion Sequences.

Publication Type: Academic Journal

Source(s): Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 Jan 24; Vol. 67 (1), pp. e0135422. Date of Electronic Publication: 2023 Jan 05.

Authors:

Abstract: The carbapenem-resistant Klebsiella pneumoniae (CRKP) strain GX34 was recovered from the respiratory tract of an elderly male with severe pneumonia, and only susceptible to amikacin, tigecycline, and colistin. Complete genome suggested that it belonged...

Detection of carbapenem-resistant hypervirulent Klebsiella pneumoniae ST11-K64 co-producing NDM-1 and KPC-2 in a tertiary hospital in Wuhan.

Publication Type: Academic Journal

Source(s): The Journal of hospital infection [J Hosp Infect] 2023 Jan; Vol. 131, pp. 70-80. Date of Electronic Publication: 2022 Sep 29.

Authors:

Abstract: Background: Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) poses serious challenges to public health. Only a few sporadic reports of strains co-producing NDM-1 and KPC-2 (NDM-1-KPC-2-CR-hvKP strains) are available to date.Objectives...

A wide clinical spectrum of pulmonary affection in subjects with community-acquired Klebsiella pneumoniae liver abscess (CA-KPLA).

Publication Type: Academic Journal

Source(s): Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2023 Jan; Vol. 29 (1), pp. 48-54. Date of Electronic Publication: 2022 Sep 18.

Authors:

Abstract: Background: Klebsiella pneumoniae is a major pathogen of bacterial liver abscess in Asia. Particularly, patients with community-acquired Klebsiella pneumoniae liver abscess (CA-KPLA) tend to have a higher risk of invasive infection and pulmonary is a c...

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