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Advanced Search Results For "neutralizing antibodies"

1 - 10 of 19,503 results for
 "neutralizing antibodies"
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Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses.

Publication Type: Academic Journal

Source(s): Nature communications [Nat Commun] 2022 Oct 21; Vol. 13 (1), pp. 6285. Date of Electronic Publication: 2022 Oct 21.

Abstract: Vaccines that are broadly cross-protective against current and future SARS-CoV-2 variants of concern (VoC) or across the sarbecoviruses subgenus remain a priority for public health. Virus neutralization is the best available correlate of protection. To...

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Combination anti-HIV antibodies provide sustained virological suppression.

Publication Type: Academic Journal

Source(s): Nature [Nature] 2022 Jun; Vol. 606 (7913), pp. 375-381. Date of Electronic Publication: 2022 Jun 01.

Abstract: Antiretroviral therapy is highly effective in suppressing human immunodeficiency virus (HIV) 1 . However, eradication of the virus in individuals with HIV has not been possible to date 2 . Given that HIV suppression requires life-long antiretroviral th...

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A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses.

Publication Type: Academic Journal

Source(s): Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 147-157.

Abstract: The repeated emergence of highly pathogenic human coronaviruses as well as their evolving variants highlight the need to develop potent and broad-spectrum antiviral therapeutics and vaccines. By screening monoclonal antibodies (mAbs) isolated from COVI...

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Dichotomy in Neutralizing Antibody Induction to Peptide-Conjugated Vaccine in Squalene Emulsion Contrast With Aluminum Hydroxide Formulation.

Publication Type: Academic Journal

Source(s): Frontiers in immunology [Front Immunol] 2022 Apr 07; Vol. 13, pp. 848571. Date of Electronic Publication: 2022 Apr 07 (Print Publication: 2022).

Abstract: W614A-3S peptide is a modified 3S motif of the HIV-gp41 (mutation W614A). We previously detected the presence of natural neutralizing antibodies directed against W614A-3S peptide (NAbs) in long-term non-progressor HIV + patients. Here, we compared the ...

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Omicron Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization by Immunoglobulin Preparations Manufactured From Plasma Collected in the United States and Europe.

Publication Type: Academic Journal

Source(s): The Journal of infectious diseases [J Infect Dis] 2022 Oct 17; Vol. 226 (8), pp. 1396-1400.

Abstract: After >2 years of the coronavirus disease 2019 (COVID-19) pandemic, immunoglobulins (IGs) contain highly potent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies, based on the large proportion of United States (US) pl...

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Neutralizing Immunity Induced Against the Omicron BA.1 and BA.2 Variants in Vaccine Breakthrough Infections.

Publication Type: Academic Journal

Source(s): The Journal of infectious diseases [J Infect Dis] 2022 Nov 11; Vol. 226 (10), pp. 1688-1698.

Abstract: Background: As of early 2022, the Omicron variants are the predominant circulating lineages globally. Understanding neutralizing antibody responses against Omicron BA.1 and BA.2 after vaccine breakthrough infections will provide insights into BA.2 infe...

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Evasion of neutralizing antibody responses by the SARS-CoV-2 BA.2.75 variant.

Publication Type: Academic Journal

Source(s): Cell host & microbe [Cell Host Microbe] 2022 Nov 09; Vol. 30 (11), pp. 1518-1526.e4. Date of Electronic Publication: 2022 Sep 28.

Abstract: The newly emerged BA.2.75 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant contains 9 additional mutations in its spike (S) protein compared to the ancestral BA.2 variant. Here, we examine the neutralizing antibody escape of BA.2.75...

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Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals.

Publication Type: Academic Journal

Source(s): Microbiology spectrum [Microbiol Spectr] 2022 Oct 26; Vol. 10 (5), pp. e0131522. Date of Electronic Publication: 2022 Sep 19.

Abstract: SARS-CoV-2 anti-spike antibody concentrations and angiotensin converting enzyme-2 (ACE-2) inhibition have been used as surrogates to live viral neutralizing antibody titers; however, validity among vaccinated individuals is unclear. We tested the corre...

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Relevant of neutralizing antibody during SARS-CoV-2 infection and their therapeutic usage.

Publication Type: Academic Journal

Source(s): Molecular biology reports [Mol Biol Rep] 2022 Oct; Vol. 49 (10), pp. 10137-10140. Date of Electronic Publication: 2022 May 21.

Authors:
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Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes.

Publication Type: Academic Journal

Source(s): Journal of structural biology [J Struct Biol] 2022 Mar; Vol. 214 (1), pp. 107839. Date of Electronic Publication: 2022 Feb 05.

Abstract: The antigenic epitope regions of pathogens (e.g., viruses) are recognized by antibodies (Abs) and subsequently cleared by the host immune system, thereby protecting us from disease. Some of these epitopes are conserved among different variants or subgr...

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