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Pneumococcal concentration and serotype distribution in preschool children with radiologically confirmed pneumonia compared to healthy controls prior to introduction of pneumococcal vaccination in Zanzibar: an observational study
Publication Type: Academic Journal
Source(s): BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract: Abstract Background The World Health Organization recommends pneumococcal vaccination (PCV) in the first year of life. We investigated pneumococcal serotypes in children with clinical or radiologically confirmed pneumonia and healthy controls prior to ...
Microbiota in the pathogenesis of COPD and its impact on the course of the disease
Publication Type: Academic Journal
Source(s): Клиническая микробиология и антимикробная химиотерапия, Vol 24, Iss 3, Pp 202-212 (2022)
Abstract: Chronic obstructive pulmonary disease (COPD) is a serious problem for global health. Infectious agents play a main role in the development of COPD exacerbations. Bacterial colonization of the lower respiratory tract is common in patients with stable CO...
Invasive Pneumococcal Disease and Long-Term Mortality Rates in Adults, Alberta, Canada
Publication Type: Academic Journal
Source(s): Emerging Infectious Diseases, Vol 28, Iss 8, Pp 1615-1623 (2022)
Abstract: The relationship between increased short-term mortality rates after invasive pneumococcal disease (IPD) has been frequently studied. However, the relationship between IPD and long-term mortality rates is unknown. IPD patients in Alberta, Canada, had cl...
Present situation of bacterial neuroinfections across the globe – review
Publication Type: Academic Journal
Source(s): Journal of Education, Health and Sport, Vol 12, Iss 10 (2022)
Abstract: Bacterial meningitis is still life-treating disease, which cause about 1.2 million cases and it is responsible for over 100 thousand of deaths across the globe. [2][ The most common pathogens which case the disease are Neisseria meningitidis, Streptoco...
Streptococcus pneumoniae - an uncommon cause of neonatal sepsis: two case reports
Publication Type: Academic Journal
Source(s): Sri Lankan Journal of Infectious Diseases, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract: Streptococcus pneumoniae is a rare but recognized aetiological agent for neonatal sepsis. In the context of scarce local data, we report two cases of early-onset neonatal sepsis (EONS) due to pneumococci that probably occurred following ascending trans...
Comparison of pneumococcal colonization density among healthy children and children with respiratory symptoms using real time PCR (RT-PCR)
Publication Type: Academic Journal
Source(s): BMC Microbiology, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract: Abstract Background Nasopharyngeal colonization is considered a necessary step in the initiation of pneumococcal diseases. Real time PCR (RT-PCR) is an alternative approach for the identification and quantification of pneumococci directly from samples....
Global genomic pathogen surveillance to inform vaccine strategies: a decade-long expedition in pneumococcal genomics
Publication Type: Academic Journal
Source(s): Genome Medicine, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract: Abstract Vaccines are powerful agents in infectious disease prevention but often designed to protect against some strains that are most likely to spread and cause diseases. Most vaccines do not succeed in eradicating the pathogen and thus allow the pot...
The expansive effects of polyamines on the metabolism and virulence of Streptococcus pneumoniae
Publication Type: Academic Journal
Source(s): Pneumonia, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract: Abstract Polyamines are common intracellular metabolites of nearly all cells, and their conservation across a vast diversity of cells suggests critical roles for these compounds in cellular physiology. Most intracellular polyamines are associated with ...
High proportion of drug-resistant isolates in adult community-acquired pneumonia from Northeast India: A hospital-based study
Publication Type: Academic Journal
Source(s): Lung India, Vol 38, Iss 5, Pp 460-465 (2021)
Abstract: Background: Empirical antibiotic therapy is the mainstay of management of adult community-acquired pneumonia (CAP) globally. Knowledge of prevalent pathogen (bacterial) profile and drug susceptibility pattern is very essential for appropriate managemen...
Molecular Epidemiology of Multidrug-Resistant Pneumococci among Ghanaian Children under Five Years Post PCV13 Using MLST
Publication Type: Academic Journal
Source(s): Microorganisms, Vol 10, Iss 469, p 469 (2022)
Abstract: Antibiotic resistance in pneumococci contributes to the high pneumococcal deaths in children. We assessed the molecular characteristics of multidrug-resistant (MDR) pneumococci isolated from healthy vaccinated children under five years of age in Cape C...