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Advanced Search Results For "spike mutation"

1 - 10 of 1,469 results for
 "spike mutation"
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Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases.

Publication Type: Academic Journal

Source(s): Journal of virology [J Virol] 2022 Mar 09; Vol. 96 (5), pp. e0218621. Date of Electronic Publication: 2022 Jan 12.

Abstract: Recent emergence of SARS-CoV-1 variants demonstrates the potential of this virus for targeted evolution, despite its overall genomic stability. Here we show the dynamics and the mechanisms behind the rapid adaptation of SARS-CoV-2 to growth in Vero E6 ...

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Role of Q675H Mutation in Improving SARS-CoV-2 Spike Interaction with the Furin Binding Pocket.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2021 Dec 14; Vol. 13 (12). Date of Electronic Publication: 2021 Dec 14.

Abstract: Genotype screening was implemented in Italy and showed a significant prevalence of new SARS-CoV-2 mutants carrying Q675H mutation, near the furin cleavage site of spike protein. Currently, this mutation, which is expressed on different SARS-CoV-2 linea...

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SARS-CoV-2 B.1.617 Mutations L452R and E484Q Are Not Synergistic for Antibody Evasion.

Publication Type: Academic Journal

Source(s): The Journal of infectious diseases [J Infect Dis] 2021 Sep 17; Vol. 224 (6), pp. 989-994.

Abstract: The SARS-CoV-2 B.1.617 variant emerged in the Indian state of Maharashtra in late 2020. There have been fears that 2 key mutations seen in the receptor-binding domain, L452R and E484Q, would have additive effects on evasion of neutralizing antibodies. ...

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Linked nosocomial COVID-19 outbreak in three facilities for people with intellectual and developmental disabilities due to SARS-CoV-2 variant B.1.1.519 with spike mutation T478K in the Netherlands.

Publication Type: Academic Journal

Source(s): BMC infectious diseases [BMC Infect Dis] 2022 Feb 10; Vol. 22 (1), pp. 139. Date of Electronic Publication: 2022 Feb 10.

Abstract: Background: Individuals with intellectual and developmental disabilities (IDD) living in congregated settings have increased risk of COVID-19 infection and mortality. Little is known about variant B.1.1.519 with spike mutation T478K, dominant in Mexico...

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.

Publication Type: Academic Journal

Source(s): Cell reports [Cell Rep] 2021 Jun 29; Vol. 35 (13), pp. 109292. Date of Electronic Publication: 2021 Jun 08.

Authors:

Abstract: We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding affinity...

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Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil.

Publication Type: Academic Journal

Source(s): Emerging infectious diseases [Emerg Infect Dis] 2021 May; Vol. 27 (5), pp. 1522-1524. Date of Electronic Publication: 2021 Feb 19.

Abstract: Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct viru...

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Structure and genome of severe acute respiratory syndrome coronavirus 2.

Publication Type: Academic Journal

Source(s): Microbes & Infectious Diseases; Aug2022, Vol. 3 Issue 3, p516-521, 6p

Abstract: Copyright of Microbes & Infectious Diseases is the property of Microbes & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, use...

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A bioinformatic analysis of the spike glycoprotein & evolution of COVID-19.

Publication Type: Academic Journal

Source(s): Medicine Science; Mar2022, Vol. 11 Issue 1, p171-175, 5p

Abstract: Copyright of Medicine Science is the property of Society of Turaz Bilim and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download...

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Linked nosocomial COVID-19 outbreak in three facilities for people with intellectual and developmental disabilities due to SARS-CoV-2 variant B.1.1.519 with spike mutation T478K in the Netherlands

Publication Type: Academic Journal

Source(s): BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)

Abstract: Abstract Background Individuals with intellectual and developmental disabilities (IDD) living in congregated settings have increased risk of COVID-19 infection and mortality. Little is known about variant B.1.1.519 with spike mutation T478K, dominant i...

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Immune Evasion of SARS-CoV-2 Omicron Subvariants

Publication Type: Academic Journal

Source(s): Vaccines, Vol 10, Iss 1545, p 1545 (2022)

Abstract: Since the SARS-CoV-2 Omicron variant (B.1.1.529) was declared a variant of concern (VOC) by the WHO on 24 November 2021, it has caused another global surge of cases. With extensive mutations in its spike glycoprotein, Omicron gained substantial capabil...

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