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Advanced Search Results For "system"

1 - 10 of 5,840,565 results for
 "system"
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The meningeal lymphatic vessels and the glymphatic system: Potential therapeutic targets in neurological disorders.

Publication Type:Academic Journal

Source(s):Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2022 Aug; Vol. 42 (8), pp. 1364-1382. Date of Electronic Publication: 2022 Apr 28.

Abstract:The recent discovery of the meningeal lymphatic vessels (mLVs) and glymphatic pathways has challenged the long-lasting dogma that the central nervous system (CNS) lacks a lymphatic system and therefore does not interact with peripheral immunity. This d...

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Essential functions of chaperones and adaptors of protein secretion systems in Gram-negative bacteria.

Publication Type:Academic Journal

Source(s):The FEBS journal [FEBS J] 2022 Aug; Vol. 289 (16), pp. 4704-4717. Date of Electronic Publication: 2021 Jun 23.

Abstract:Equipped with a plethora of secreted toxic effectors, protein secretion systems are essential for bacteria to interact with and manipulate their neighboring environment to survive in host microbiota and other highly competitive communities. While effec...

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Autonomic function testing in multiple system atrophy: a prognostic biomarker? and other updates on recent autonomic research.

Publication Type:Editorial & Opinion

Source(s):Clinical autonomic research : official journal of the Clinical Autonomic Research Society [Clin Auton Res] 2022 Aug; Vol. 32 (4), pp. 219-221. Date of Electronic Publication: 2022 Jul 30.

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Lipid nanoparticles strategies to modify pharmacokinetics of central nervous system targeting drugs: Crossing or circumventing the blood-brain barrier (BBB) to manage neurological disorders.

Publication Type:Academic Journal

Source(s):Advanced drug delivery reviews [Adv Drug Deliv Rev] 2022 Oct; Vol. 189, pp. 114485. Date of Electronic Publication: 2022 Aug 12.

Abstract:The main limitation to the success of central nervous system (CNS) therapies lies in the difficulty for drugs to cross the blood-brain barrier (BBB) and reach the brain. Regarding its structure and enzymatic complexity, crossing the BBB is a challenge,...

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miR-124: A Promising Therapeutic Target for Central Nervous System Injuries and Diseases.

Publication Type:Academic Journal

Source(s):Cellular and molecular neurobiology [Cell Mol Neurobiol] 2022 Oct; Vol. 42 (7), pp. 2031-2053. Date of Electronic Publication: 2021 Apr 22.

Abstract:Central nervous system injuries and diseases, such as ischemic stroke, spinal cord injury, neurodegenerative diseases, glioblastoma, multiple sclerosis, and the resulting neuroinflammation often lead to death or long-term disability. MicroRNAs are smal...

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Correlation between clinical severity and extent of autonomic cardiovascular impairment in the acute phase of subarachnoid hemorrhage.

Publication Type:Academic Journal

Source(s):Journal of neurology [J Neurol] 2022 Oct; Vol. 269 (10), pp. 5541-5552. Date of Electronic Publication: 2022 Jun 20.

Abstract:Background and Aim: To assess associations between clinical severity and possible dysfunction of autonomic cardiovascular modulation within the acute phase after spontaneous subarachnoid hemorrhage (SAH).Methods: In this prospective observational study...

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Ocular Lymphatic and Glymphatic Systems: Implications for Retinal Health and Disease.

Publication Type:Academic Journal

Source(s):International journal of molecular sciences [Int J Mol Sci] 2022 Sep 04; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 04.

Abstract:Clearance of ocular fluid and metabolic waste is a critical function of the eye in health and disease. The eye has distinct fluid outflow pathways in both the anterior and posterior segments. Although the anterior outflow pathway is well characterized,...

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The food preservative sodium propionate induces hyperglycaemic state and neurological disorder in zebrafish.

Publication Type:Academic Journal

Source(s):Neurotoxicology and teratology [Neurotoxicol Teratol] 2022 Sep-Oct; Vol. 93, pp. 107123. Date of Electronic Publication: 2022 Sep 21.

Abstract:Propionate is an effective mould inhibitor widely used as a food preservative. In this study, we used zebrafish to explore the adverse effects of long-term exposure to low concentrations of sodium propionate and the underlying molecular mechanisms (fro...

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Potential mechanism of SARS-CoV-2-associated central and peripheral nervous system impairment.

Publication Type:Academic Journal

Source(s):Acta neurologica Scandinavica [Acta Neurol Scand] 2022 Sep; Vol. 146 (3), pp. 225-236. Date of Electronic Publication: 2022 Jun 14.

Abstract:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is more than merely a respiratory disease, as it also presents with various neurological symptoms. SARS-CoV-2 may infect the central nervous system (CNS) and thus is neurotropic. However, the...

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A systematic review and meta-analysis of the association between parenting and child autonomic nervous system activity.

Publication Type:Academic Journal

Source(s):Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2022 Aug; Vol. 139, pp. 104734. Date of Electronic Publication: 2022 Jun 15.

Abstract:Parental socialization may influence the development of children's autonomic nervous system (ANS), a key stress-response system. However, to date no quantitative synthesis of the literature linking parenting and child ANS physiology has been conducted....

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