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Advanced Search Results For "type 2 diabetes mellitus"

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 "type 2 diabetes mellitus"
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A combination of exercise and calorie restriction improves the development of obesity-related type 2 diabetes mellitus in KKAy mice.

Publication Type: Academic Journal

Source(s): Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2022 Dec 21; Vol. 87 (1), pp. 108-113.

Abstract: We observed that exercise and calorie restriction reduced the body weight and blood glucose levels, concurrently improving insulin resistance and glucose tolerance in obese/diabetic model KKAy mice. Analysis of gene expression in the skeletal muscle sh...

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Peptide Tyrosine-Tyrosine Triggers GLP-2-Mediated Intestinal Hypertrophy After Roux-en-Y Gastric Bypass.

Publication Type: Academic Journal

Source(s): Obesity surgery [Obes Surg] 2022 Dec; Vol. 32 (12), pp. 4023-4032. Date of Electronic Publication: 2022 Oct 27.

Abstract: PURPOSE : Intestinal remodeling and adaptation of the alimentary limb after Roux-en-Y gastric bypass (RYGB) play an important role in the pathophysiological events that lead to type 2 diabetes mellitus (T2DM) improvement. Intestinal absorptive loop hyp...

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Islet MC4R Regulates PC1/3 to Improve Insulin Secretion in T2DM Mice via the cAMP and β-arrestin-1 Pathways.

Publication Type: Academic Journal

Source(s): Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2022 Dec; Vol. 194 (12), pp. 6164-6178. Date of Electronic Publication: 2022 Jul 28.

Authors:

Abstract: Melanocortin-4 receptor (MC4R) plays an important role in energy balance regulation and insulin secretion. It has been demonstrated that in the pancreas, it is expressed in islet α and β cells, wherein it is significantly correlated with insulin and gl...

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Mother-Infant Dyad program in primary care: evidence-based postpartum care following gestational diabetes.

Publication Type: Academic Journal

Source(s): The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2022 Dec; Vol. 35 (25), pp. 9336-9341. Date of Electronic Publication: 2022 Jan 30.

Abstract: Background: Gestational diabetes mellitus (GDM), a common complication of pregnancy, is associated with a 10-fold increased risk of type 2 diabetes mellitus (T2DM) compared to the general population. Evidence-based guidelines recommend that patients wi...

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Rhamnogalacturonan-I enriched pectin from steamed ginseng ameliorates lipid metabolism in type 2 diabetic rats via gut microbiota and AMPK pathway.

Publication Type: Academic Journal

Source(s): Journal of ethnopharmacology [J Ethnopharmacol] 2023 Jan 30; Vol. 301, pp. 115862. Date of Electronic Publication: 2022 Oct 22.

Authors:

Abstract: Ethnopharmacological Relevance: Panax ginseng C. A. Meyer (Ginseng) has traditionally been used to treat diabetes. Polysaccharide is the main active component of ginseng, and has been proved to have hypoglycaemic and hypolipidaemic effects, but its mec...

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Characterization of antidiabetic effects of Dendrobium officinale derivatives in a mouse model of type 2 diabetes mellitus.

Publication Type: Academic Journal

Source(s): Food chemistry [Food Chem] 2023 Jan 15; Vol. 399, pp. 133974. Date of Electronic Publication: 2022 Aug 17.

Authors:

Abstract: In this research, two sequential Dendrobium officinale water extracts (WDOE and WDOP1) were shown to significantly ameliorate type 2 diabetic mellitus (T2DM) in a mouse model. WDOP1 was identified as a glucomannan with a backbone of 1,4-linked Manp and...

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Canagliflozin promotes osteoblastic MC3T3-E1 differentiation via AMPK/RUNX2 and improves bone microarchitecture in type 2 diabetic mice.

Publication Type: Academic Journal

Source(s): Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Dec 16; Vol. 13, pp. 1081039. Date of Electronic Publication: 2022 Dec 16 (Print Publication: 2022).

Authors:

Abstract: Individuals with type 2 diabetes mellitus (T2DM) have an increased risk of bone metabolic disorders and bone fracture due to disease progression and clinical treatment. The effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors, now greatly prescr...

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A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia.

Publication Type: Academic Journal

Source(s): Experimental animals [Exp Anim] 2022 Nov 10; Vol. 71 (4), pp. 510-518. Date of Electronic Publication: 2022 Jul 28.

Abstract: Various mouse models of type 2 diabetes have been established, but few of these show early onset and persistent hyperglycemia. We have established a congenic mouse strain (NSY.B6-Tyr + ,A y ) in which a spontaneous mutation of the agouti yellow (A y ) ...

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In-depth investigation of the hypoglycemic mechanism of Morchella importuna polysaccharide via metabonomics combined with 16S rRNA sequencing.

Publication Type: Academic Journal

Source(s): International journal of biological macromolecules [Int J Biol Macromol] 2022 Nov 01; Vol. 220, pp. 659-670. Date of Electronic Publication: 2022 Aug 19.

Authors:

Abstract: Increasing evidence indicates that type 2 diabetes mellitus (T2DM) is closely related to intestinal bacteria disorders and abnormal hepatic metabolism. Morchella importuna polysaccharide (MIP) shows excellent hypoglycemic activity in vitro. However, th...

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Sodium-glucose cotransporter 2 inhibitors for non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus: A nationwide propensity-score matched cohort study.

Publication Type: Academic Journal

Source(s): Diabetes research and clinical practice [Diabetes Res Clin Pract] 2022 Dec; Vol. 194, pp. 110187. Date of Electronic Publication: 2022 Nov 26.

Authors:

Abstract: Aims: This study was to determine the association between sodium-glucose cotransporter 2 inhibitors (SGLT2i) and nonalcoholic fatty liver disease (NAFLD) in type 2 diabetes.Methods: We used data from the Korean National Health Insurance Service from 20...

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