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Estimating inter-patient variability of dispersion in dry powder inhalers using CFD-DEM simulations.

Publication Type: Academic Journal

Source(s): European Journal of Pharmaceutical Sciences. Jan2021, Vol. 156, pN.PAG-N.PAG. 1p.

Abstract: Drug delivery from a capsule-based dry powder inhaler depends on the inhaler's design, the drug's formulation, and the inhalation maneuver. The latter affects both the air flow and the capsule motion in the inhaler. It is well known that patient-to-pat...

Prediction of Inter-particle Adhesion Force from Surface Energy and Surface Roughness.

Publication Type: Academic Journal

Source(s): Journal of Adhesion Science & Technology. 2011, Vol. 25 Issue 4/5, p367-384. 18p. 1 Black and White Photograph, 3 Charts, 7 Graphs.

Abstract: Fine powder flow is a topic of great interest to industry, in particular for the pharmaceutical industry; a major concern being their poor flow behavior due to high cohesion. In this study, cohesion reduction, produced via surface modification, at the ...

Assessment of Cytocompatibility and Anti-Inflammatory (Inter)Actions of Genipin-Crosslinked Chitosan Powders.

Publication Type: Academic Journal

Source(s): Biology (2079-7737). Jul2020, Vol. 9 Issue 7, p159. 1p.

Abstract: Chitosan is a polysaccharide commonly used, together with its derivatives, in the preparation of hydrogel formulations, scaffolds and films for tissue engineering applications. Chitosan can be used as such, but it is commonly stabilized by means of che...

Enhanced Permeability of Fe-Based Amorphous Powder Cores Realized through Selective Incorporation of Carbonyl Iron Powders at Inter-Particle Voids.

Publication Type: Academic Journal

Source(s): Metals (2075-4701). Aug2021, Vol. 11 Issue 8, p1220. 1p.

Abstract: In this study, we demonstrate a hybrid multimodal soft magnetic composite (SMC) comprising gas-atomized spherical amorphous powder (AP) and carbonyl-iron powder (CIP), and present its enhanced electromagnetic properties. CIP is selectively incorporated...

Removal of geosmin with inter-chlorination using powdered activated carbon in full-scale WTP.

Publication Type: Academic Journal

Source(s): Desalination & Water Treatment; Mar2015, Vol. 53 Issue 10, p2850-2855, 6p


Abstract: Copyright of Desalination & Water Treatment is the property of Balaban Publishers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print...

On the relationship of inter-particle cohesiveness and bulk powder behavior: Flowability of pharmaceutical powders.

Publication Type: Academic Journal

Source(s): International journal of pharmaceutics [Int J Pharm] 2016 Sep 10; Vol. 511 (1), pp. 178-189. Date of Electronic Publication: 2016 Jun 25.

Abstract: This study investigates the relationship between particle interactions dominated by the cohesive van der Waals force and powder flowability for materials commonly used by the pharmaceutical industry in oral solid dosage formulation. This study first so...

Evaluation of critical process parameters for inter-tablet coating uniformity of active-coated GITS using Terahertz Pulsed Imaging.

Publication Type: Academic Journal

Source(s): European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2014 Oct; Vol. 88 (2), pp. 434-42. Date of Electronic Publication: 2014 Jul 15.

Abstract: The aim of this study was the evaluation of critical process parameters (CPP) for inter-tablet coating uniformity in an active pan coating process using nondestructive Terahertz Pulsed Imaging (TPI). Coating uniformity was assessed by calculating the c...

Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery.

Publication Type: Academic Journal

Source(s): International journal of cosmetic science [Int J Cosmet Sci] 2012 Dec; Vol. 34 (6), pp. 525-35. Date of Electronic Publication: 2012 Oct 11.

Abstract: Twenty products, containing a radiolabelled form of each active in typical cosmetic formulations, were made and applied to female human epidermal membranes mounted in Franz diffusion cells for 48 h under 'in use' conditions. The products consisted of c...

Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.

Publication Type: Academic Journal

Source(s): Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2012 Jan 01; Vol. 22 (1), pp. 313-8. Date of Electronic Publication: 2011 Nov 10.

Abstract: The synthesis of nine bivalent lactosides (based on ditriazoles, diamides, a glycocyclophane and an acyclic analogue of the glycocyclophane) and one monovalent lactosyl triazole facilitated the assessment of the sensitivity of plant/animal lectins to t...

Inter- and intra-manufacturer variability in pharmaceutical grades and lots of xanthan gum.

Publication Type: Academic Journal

Source(s): AAPS PharmSciTech [AAPS PharmSciTech] 2010 Dec; Vol. 11 (4), pp. 1619-26. Date of Electronic Publication: 2010 Nov 18.

Abstract: A pharmaceutical formulation typically contains one or more excipients in addition to the active pharmaceutical ingredient(s). Though excipients have been considered inert components of a formulation, variability in their properties has been shown to a...